ArticleBMC microbiology2019
Effect of tetracycline treatment regimens on antibiotic resistance gene selection over time in nursery pigs.
Article in BMC microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 53 citations in OpenAlex.
- Longitudinal investigation of the resistomes in Swedish pig farms.npj antimicrobials and resistance · 2026Article
- Temporal dynamics of the resistome in gilts raised in an organic operation in which semen used for artificial insemination is the primary source of antimicrobial exposure.Scientific reports · 2025Article
- Virulence plasmids in edema disease: Insights from whole-genome analysis of porcine O139:H1 Shiga toxin-producingFrontiers in cellular and infection microbiology · 2025Article
- Antimicrobial resistance genes in weaned pigs: quantitative abundance and group dynamics assessed by qPCR.Frontiers in veterinary science · 2025Article
- Resistomes from oxytetracycline-treated pigs are readily transferred to untreated pen mates.Animal microbiome · 2024Article
- Molecular characterization of Streptococcus suis isolates recovered from diseased pigs in Europe.Veterinary research · 2024Article
- Whole-genome sequencing of multidrug-resistant Klebsiella pneumoniae with capsular serotype K2 isolates from mink in China.BMC veterinary research · 2024Article
- Molecular Characterisation of Antimicrobial Resistance inAntibiotics (Basel, Switzerland) · 2023Article
- The effects of antibiotic use on the dynamics of the microbiome and resistome in pigs.Animal microbiome · 2023Article
- National Monitoring of Veterinary-Dispensed Antimicrobials for Use on Pig Farms in Austria: 2015-2020.Antibiotics (Basel, Switzerland) · 2022Article
- Evaluation of the Impact of Antimicrobial Use Protocols in Porcine Reproductive and Respiratory Syndrome Virus-Infected Swine on Phenotypic Antimicrobial Resistance Patterns.Applied and environmental microbiology · 2022Article
- Epidemiology, Environmental Risks, Virulence, and Resistance Determinants ofFrontiers in microbiology · 2022Article
- Parasitic Intestinal Protists of Zoonotic Relevance Detected in Pigs by Metabarcoding and Real-Time PCR.Microorganisms · 2021Article
- Replacement of Metaphylactic Antimicrobial Therapy by Oral Administration ofFrontiers in veterinary science · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe majority of antimicrobials given during the production of pigs are given to nursery pigs. The influence of antimicrobial use on the levels of antimicrobial resistant (AMR) genes is important to quantify to be able to assess the impact of resistance on the food chain and risk to human and animal health.
resultsThis study investigated the response on the levels of nine AMR genes to five different treatment strategies with oxytetracycline, and the dynamics of gene abundance over time by following 1167 pigs from five different farms in Denmark. The results showed no significant difference between treatments and an increase in abundance for the efflux pump encoding tet(A) gene and the genes encoding the ribosomal protection proteins tet(O) and tet(W) tetracycline resistant genes following treatment, while tet(M) showed no response to treatment. However, it was also observed that the levels of tet(O), tet(W), and ermB in some farms would drift more over time compared to a single treatment-course with antibiotic.
conclusionThis study underlines the large variation in AMR levels under natural conditions and the need for increased investigation of the complex interactions of antimicrobial treatment and other environmental and managerial practices in swine production on AMR gene abundance.
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