Evidence map›Paper›PMID 31790953›Full record

ReviewCell calcium2020

Type 3 inositol 1,4,5-trisphosphate receptor: A calcium channel for all seasons.

Anjali Mangla, Mateus T Guerra, Michael H Nathanson

Open access · greenAbstract readReview
In one paragraph

Review in Cell calcium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Cannabidiol-Ion Channel Interactions Represent a Promising Preventive and Therapeutic Strategy in Hepatocellular Carcinoma.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Impact of static magnetic field exposure onJournal of advanced veterinary and animal research · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. A frameshift mutation in the murinebioRxiv : the preprint server for biology · 2024
    Article
  20. Translational cancer research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anjali ManglaSection of Digestive Diseases, Department of Internal Medicine, Yale School of Medicine, USA.
Mateus T GuerraSection of Digestive Diseases, Department of Internal Medicine, Yale School of Medicine, USA.
Michael H NathansonSection of Digestive Diseases, Department of Internal Medicine, Yale School of Medicine, USA. Electronic address: michael.nathanson@yale.edu.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Liver CenterP30DK034989 · NIDDK · YALE UNIVERSITY · PI YASUKO IWAKIRI · 1986 to 2026
$31.1M
Translational CoreP01DK057751 · NIDDK · YALE UNIVERSITY · PI YANG, XIAOYONG · 2001 to 2020
$25.6M
Ca2+ waves in hepatocytes: Mechanisms and effectsR01DK114041 · NIDDK · YALE UNIVERSITY · PI NATHANSON, MICHAEL H · 2018 to 2022
$2.6M
Molecular regulation of cholestasis in cholangiocytesR01DK112797 · NIDDK · YALE UNIVERSITY · PI NATHANSON, MICHAEL H · 2018 to 2021
$1.9M
A super-resolution microscope for research and educationS10OD020142 · OD · YALE UNIVERSITY · PI NATHANSON, MICHAEL H · 2015 to 2015
$600k
NCATS NIH HHS UL1 TR001863NIDDK NIH HHS P01 DK057751NIDDK NIH HHS P30 DK034989NIDDK NIH HHS R01 DK112797NIDDK NIH HHS R01 DK114041NIH HHS S10 OD020142
6 · The paper itself

Abstract

Inositol 1,4,5 trisphosphate receptors (ITPRs) are a family of endoplasmic reticulum Ca

Indexed as

AnimalsBiophysical PhenomenaCalcium ChannelsDiseaseEndoplasmic ReticulumHumansInositol 1,4,5-Trisphosphate ReceptorsMitochondriaModels, BiologicalCalcium ChannelsInositol 1,4,5-Trisphosphate ReceptorsApoptosisCancerCholestasisInositol 1,4,5-trisphosphate receptorPromoter methylation

Identifiers

PMID31790953
PMCPMC6917836
OpenAlexW2990089416

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.