ArticleAging2019
Parity is associated with albuminuria and chronic kidney disease: a population-based study.
Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Long-term impact of pregnancy on mortality and graft outcomes in kidney transplant recipients: a systematic review and meta-analysis.International urology and nephrology · 2025Pooled it
- A systematic review examining the association between parity and gravidity & hypertension and blood pressure.NPJ cardiovascular health · 2026Article
- Association between the number of pregnancies and hearing loss: NHANES 1999-2018.BMC public health · 2025Article
- Relationship between parity and the prevalence of chronic kidney disease in Japan considering hypertensive disorders of pregnancy and body mass index.BMC nephrology · 2024Article
- Sonographic Evaluation of Maternal Renal Echogenicity in Healthy Pregnant Women in the Niger Delta Region of Nigeria.Ethiopian journal of health sciences · 2023Article
- Parity and hypertension risk in couples: does number of parity matter: findings from Tehran Lipid and Glucose Study.BMC public health · 2023Article
- Graft function and pregnancy outcomes after kidney transplantation.BMC nephrology · 2022Observational
- Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsEpidemiological studies have shown that increasing parity is associated with risk of hypertension and diabetes in parous women. However, the relationship between the parity degree with chronic kidney disease (CKD) is still unknown.
resultsParous women with higher parity had increased age, body mass index, waist circumference, systolic blood pressure, fasting plasma glucose, fasting insulin and decreased high-density lipoprotein cholesterol, eGFR and education levels. Compared with women with one-child birth, those with more than two-child births had greater prevalence of increased urinary albumin excretion (odds ratios [ORs] 1.53, 95% confidence intervals [CI], 1.03 - 2.28) and CKD (ORs 1.79, 95% CI, 1.24 - 2.58) after multiple adjustments. In dose-response analysis, a nonlinear relationship of parity degree with albuminuria and CKD was detected.
conclusionParity is associated with higher prevalence of albuminuria and CKD in middle-aged and elderly Chinese women.
methodsWe conducted a community-based study in 6,946 women to investigate the association of parity with albuminuria and CKD. Increased urinary albumin excretion was defined as albumin-to-creatinine ratio (ACR) greater or equal than 30 mg/g. CKD was defined as estimated glomerular filtration rate (eGFR) less than 60 mL/min per 1.73 m² or presence of albuminuria.
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