Evidence map›Paper›PMID 31790338›Full record

ArticlePhysiological genomics2020

Striated muscle-specific serine/threonine-protein kinase beta segregates with high versus low responsiveness to endurance exercise training.

Denis Kusić, Joanne Connolly, Heikki Kainulainen, Ekaterina A Semenova, Oleg V Borisov, Andrey K Larin, Daniil V Popov, Edward V Generozov, Ildus I Ahmetov, Steven L Britton and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Physiological genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 5 countries.

Denis KusićResearch Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.
Joanne ConnollyWaters Ltd, Wilmslow, Manchester, United Kingdom.
Heikki KainulainenFaculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
Ekaterina A SemenovaDepartment of Molecular Biology and Genetics, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia.
Oleg V BorisovDepartment of Molecular Biology and Genetics, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia.
Andrey K LarinDepartment of Molecular Biology and Genetics, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia.
Daniil V PopovLaboratory of Exercise Physiology, Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Russia.ORCID 0000-0002-3981-244X
Edward V GenerozovDepartment of Molecular Biology and Genetics, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow, Russia.
Ildus I AhmetovResearch Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.
Steven L BrittonDepartment of Anaesthesiology, University of Michigan, Ann Arbor, Michigan.
Lauren G KochDepartment of Physiology and Pharmacology, The University of Toledo, Toledo, Ohio.
Jatin G BurnistonResearch Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.ORCID 0000-0001-7303-9318
Federal Medical-Biological Agency · RULiverpool John Moores University · GBInstitute of Biomedical Problems · RUKazan State Medical University · RUUniversity Hospital Bonn · DEUniversity of Jyväskylä · FIUniversity of Michigan · USUniversity of Toledo · USWaters (United Kingdom) · GB

Funding

Resource for Rat Genetic Models of Aerobic CapacityP40OD021331 · OD · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI KOCH, LAUREN GERARD · 2015 to 2019
$1.9M
NIH HHS P40 OD021331
6 · The paper itself

Abstract

Bidirectional selection for either high or low responsiveness to endurance running has created divergent rat phenotypes of high-response trainers (HRT) and low-response trainers (LRT). We conducted proteome profiling of HRT and LRT gastrocnemius of 10 female rats (body weight 279 ± 35 g;

Indexed as

Physical Conditioning, AnimalAnimalsFemaleGene FrequencyGlycolysisHumansMaleMuscle ProteinsMuscle, SkeletalMuscle, StriatedOrgan SpecificityPolymorphism, Single NucleotideProtein Interaction MapsProtein KinasesProtein Serine-Threonine KinasesRatsMuscle ProteinsProtein KinasesProtein Serine-Threonine KinasesSPEG protein, humanSpeg protein, ratartificial selection modelcoimmunoprecipitationendurance trainingexercise capacitylabel-free quantitationliquid chromatography mass spectrometryresponsiveness to exerciseskeletal muscle

Identifiers

PMID31790338
PMCPMC6985788
OpenAlexW2992113269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.