ArticleNano letters2019
Circular Dichroism Measurement of Single Metal Nanoparticles Using Photothermal Imaging.
Article in Nano letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 90 citations in OpenAlex.
- Dual-parameter chiral detection at the single-particle level enabled by surface cosine waves.Science advances · 2026Article
- Four in One: Parallel Determination of Optical Activity and Optical Anisotropy from Single Plasmonic Nanostructures.ACS nano · 2026Article
- Chiral nanoparticles drive enantiomer-specific osteogenic differentiation of stem cells and accelerate bone regeneration.Science advances · 2026Article
- High-Sensitivity Detection of Chiro-Optical Effects in Single Nanoparticles by Four-Wave Mixing Interferometry.ACS photonics · 2025Article
- Nanophotonic-Enhanced Thermal Circular Dichroism for Chiral Sensing.ACS photonics · 2025Article
- Chiral plasmonic nanostructures fabricated with circularly polarized light.Beilstein journal of nanotechnology · 2025Review
- Single-Particle Photothermal Circular Dichroism and Photothermal Magnetic Circular Dichroism Microscopy.Nano letters · 2024Review
- Nanomechanical Photothermal Near Infrared Spectromicroscopy of Individual Nanorods.ACS photonics · 2023Article
- Optical Monitoring of the Magnetization Switching of Single Synthetic-Antiferromagnetic Nanoplatelets with Perpendicular Magnetic Anisotropy.ACS photonics · 2023Article
- Distinguishing Single-Metal Nanoparticles with Subdiffraction Spatial Resolution Using Variable-Polarization Fourier Transform Nonlinear Optical Microscopy.Chemical & biomedical imaging · 2023Article
- Thousand-Fold Enhancement of Photothermal Signals in Near-Critical COThe journal of physical chemistry. C, Nanomaterials and interfaces · 2023Article
- Photothermal Circular Dichroism Measurements of Single Chiral Gold Nanoparticles Correlated with Electron Tomography.ACS photonics · 2022Article
- Optically Probing the Chirality of Single Plasmonic Nanostructures and of Single Molecules: Potential and Obstacles.ACS photonics · 2022Review
- Imaging the Magnetization of Single Magnetite Nanoparticle Clusters via Photothermal Circular Dichroism.Nano letters · 2022Article
- Quantification of the Helical Morphology of Chiral Gold Nanorods.ACS materials letters · 2022Article
- Plasmon-Mediated Chiroptical Second Harmonic Generation from Seemingly Achiral Gold Nanorods.ACS nanoscience Au · 2022Article
- Local controllability of hot electron and thermal effects enabled by chiral plasmonic nanostructures.Nanophotonics (Berlin, Germany) · 2022Article
- Optical Microscopy Systems for the Detection of Unlabeled Nanoparticles.International journal of nanomedicine · 2022Review
- Photothermal Spectro-Microscopy as Benchmark for Optoplasmonic Bio-Detection Assays.The journal of physical chemistry. C, Nanomaterials and interfaces · 2021Article
- Photothermal Circular Dichroism of Single Nanoparticles Rejecting Linear Dichroism by Dual Modulation.ACS nano · 2021Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circular dichroism (CD) spectroscopy is a powerful optical technique for the study of chiral materials and molecules. It gives access to an enantioselective signal based on the differential absorption of right and left circularly polarized light, usually obtained through polarization analysis of the light transmitted through a sample of interest. CD is routinely used to determine the secondary structure of proteins and their conformational state. However, CD signals are weak, limiting the use of this powerful technique to ensembles of many molecules. Here, we experimentally realize the concept of photothermal circular dichroism, a technique that combines the enantioselective signal from circular dichroism with the high sensitivity of photothermal microscopy, achieving a superior signal-to-noise ratio to detect chiral nano-objects. As a proof of principle, we studied the chiral response of single plasmonic nanostructures with CD in the visible range, demonstrating a signal-to-noise ratio better than 40 with only 30 ms integration time for these nanostructures. The high signal-to-noise ratio allows us to quantify the CD signal for individual nanoparticles. We show that we can distinguish relative absorption differences for right circularly and left circularly polarized light as small as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.