ReviewOtology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology2020
Sex-based Differences in Hearing Loss: Perspectives From Non-clinical Research to Clinical Outcomess.
Review in Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed.
- An external focus promotes motor learning of an aiming task in individuals with hearing impairments.European journal of sport science · 2024Trial
- Quantifying What Better-Ear PTA4 Does Not Capture: High-Frequency and Asymmetric Classification Discordance in Two Independent Adult Population Samples from Germany and the United States.Audiology research · 2026Article
- Validation of the Shoebox PureTest audiometry technology for remote data collection in clinical trials.Scientific reports · 2026Article
- Associations Between Neuropathy, Nephropathy and Hearing Loss in Individuals with Type 2 Diabetes.Biomedicines · 2026Article
- Cochlear histopathology in macaques after noise-induced temporary threshold shifts.Hearing research · 2026Article
- The Influence of Sex, Ear, and Age on Auditory Brainstem Responses Recorded with the NeuroAudio System.Diagnostics (Basel, Switzerland) · 2026Article
- Associations of combined hearing loss and depression with cognitive impairment among older adults: a sex difference analysis based on evidence from CHARLS.BMC public health · 2026Article
- Furosemide prevents noise-induced hearing loss and enhances the preventive effect of N-acetylcysteine.Hearing research · 2026Article
- Persistent impairment of spatial hearing and neural binaural interaction after "temporary" noise-induced hearing loss.bioRxiv : the preprint server for biology · 2026Article
- Portable automated rapid testing for auditory assessment: repeated at-home testing in older adults.Frontiers in digital health · 2026Article
- Sex differences in response to kanamycin-induced ototoxicity in C57BL/6 J mice.Scientific reports · 2025Article
- Patterns and Severity of Hearing Loss in Patients Undergoing Pure Tone Audiometry in Eastern Nepal: An Observational Study.JNMA; journal of the Nepal Medical Association · 2025Observational
- Associations Between Occupational Noise Exposure, Aging, and Gender and Hearing Loss: A Cross-Sectional Study in China.Audiology research · 2025Article
- The Stigma of Hearing Loss: A Scoping Review of the Literature Across Age and Gender.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Evaluation of the Decrease in DPOAE Levels After VEMP Testing in Clinical Patients Referred to the Vertigo Outpatient Clinic.Journal of clinical medicine · 2025Article
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- Exploring the association between secondhand smoke exposure and hearing loss among U.S. nonsmokers.PloS one · 2025Article
- Cognitive Disorders In Acquired Sensorineural Hearing Loss, At The Ent Department Of The "Village Bondeko" Center, In Kinshasa.Neuropsychiatric disease and treatment · 2025Article
- A descriptive epidemiological study of the prevalence of self-reported sensory difficulties by age group, sex, education, disability, and migration status in Sweden in 2020.BMC public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionIt is estimated over 466 million people worldwide have disabling hearing loss, and untreated hearing loss is associated with poorer health outcomes. The influence of sex as a biological variable on hearing loss is not well understood, especially for differences in underlying mechanisms which are typically elucidated through non-clinical research. Although the inclusion of sex as a biological variable in clinical studies has been required since 1993, sex reporting has only been recently mandated in National Institutes of Health funded non-clinical studies.
objectiveThis article reviews the literature on recent non-clinical and clinical research concerning sex-based differences in hearing loss primarily since 1993, and discusses implications for knowledge gaps in the translation from non-clinical to clinical realms.
conclusionsThe disparity between sex-based requirements for non-clinical versus clinical research may inhibit a comprehensive understanding of sex-based mechanistic differences. Such disparities may play a role in understanding and explaining clinically significant sex differences and are likely necessary for developing robust clinical treatment options.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.