Evidence map›Paper›PMID 31789536›Full record

ArticleBehavioral neuroscience2020

The medial prefrontal cortex is needed for resolving interference even when there are no changes in task rules and strategies.

Gregory J Peters, David M Smith

Abstract read
In one paragraph

Article in Behavioral neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Aging is not equal across memory systems.Neurobiology of learning and memory · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gregory J PetersDepartment of Psychology.
David M SmithDepartment of Psychology.ORCID 0000-0002-5156-8099

Funding

Hippocampus, Retrosplenial Cortex and Contextual Learning and MemoryR01MH083809 · NIMH · CORNELL UNIVERSITY · PI SMITH, DAVID M., WARDEN, MELISSA RHOADS · 2010 to 2022
$3.6M
NIH HHSNIMH NIH HHS R01 MH083809
6 · The paper itself

Abstract

The prefrontal cortex (PFC) plays a key role in behavioral flexibility, and the ability to resolve conflict from shifting strategies, task rules or attentional demands seems to be a hallmark of PFC function. Conflict also occurs in the domain of memory and the PFC plays an important role in the ability to cope with interference between competing retrieval targets. Previous studies often involved both interference and changes in task demands, which makes it difficult to determine the degree to which mnemonic interference per se engages PFC processing. We trained rats on a continuous matching to sample task in two conditions that varied in terms of the amount of interference present but not the task demands and found that temporary inactivation of the medial PFC caused a greater impairment in the high-interference condition. This result suggests that the PFC plays an important role in resolving interference which can be distinguished from its role in shifting task demands. (PsycINFO Database Record (c) 2020 APA, all rights reserved).

Indexed as

AnimalsAttentionCuesHippocampusMaleMemoryOdorantsPrefrontal CortexRatsRats, Long-Evans

Identifiers

PMID31789536
PMCPMC6944745

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.