Evidence map›Paper›PMID 31789481›Full record

Observational studyCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2020

Two decades after coronary radiation therapy: A single center longitudinal clinical study.

Sumant P Radhoe, Anne-Sophie Schuurman, Jurgen M Ligthart, Karen Witberg, Peter P T de Jaegere, Ron T van Domburg, Evelyn Regar

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Two decades after coronary radiation therapy: A single center longitudinal clinical study.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2020
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sumant P RadhoeDepartment of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
Anne-Sophie SchuurmanDepartment of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
Jurgen M LigthartDepartment of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID 0000-0002-2544-5255
Karen WitbergDepartment of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
Peter P T de JaegereDepartment of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
Ron T van DomburgDepartment of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID 0000-0003-3551-133X
Evelyn RegarUniversity Heart Center, University Hospital Zürich, Zürich, Switzerland.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate the very long-term clinical outcome after radioactive stent (RS) implantation and intracoronary β radiation brachytherapy (IRBT).

backgroundRadioactive stents (RS) and intracoronary β radiation brachytherapy (IRBT) were introduced to prevent restenosis after percutaneous coronary intervention (PCI). Both techniques were associated with a higher incidence of major adverse cardiac events (MACE) in the short and intermediate-term follow up as compared to conventional PCI.

methodsOne hundred and thirty-three patients received radioactive stents (

resultsMedian follow-up duration was 17 years. All-cause mortality rates were similar in all groups. Adjusted hazard ratios for MACE and mortality in the RS cohort were 1.55 (95% CI 1.20-2.00) and 0.92 (95% CI 0.63-1.34), respectively. Adjusted hazard ratios for MACE and all-cause mortality in the IRBT cohort were 1.41 (95% CI 1.18-1.67) and 0.95 (95% CI 0.74-1.21), respectively. The difference in MACE rates was predominantly driven by coronary revascularizations in both groups, with a higher MI rate in the IRBT group as well.

conclusionsCoronary radiation therapy was associated with early increased MACE rates, but the difference in MACE rates decreased beyond 2 years, resulting in a comparable long-term clinical outcome. Importantly, no excess in mortality was observed.

Indexed as

BrachytherapyStentsAgedCase-Control StudiesCoronary Artery DiseaseCoronary RestenosisFemaleHumansLongitudinal StudiesMaleMiddle AgedNetherlandsPercutaneous Coronary InterventionRisk AssessmentRisk FactorsTime Factorsbrachytherapycoronary artery diseasepercutaneous coronary intervention (PCI)restenosis

Identifiers

PMID31789481
PMCPMC7540400
OpenAlexW2989589603

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.