Evidence map›Paper›PMID 31789479›Full record

ArticleMolecular nutrition & food research2020

Novel Resistant Starch Type 4 Products of Different Starch Origins, Production Methods, and Amounts Are Not Equally Fermented when Fed to Sprague-Dawley Rats.

Diana B Coulon, Ryan Page, Anne M Raggio, Justin Guice, Brain Marx, Vishnupriya Gourineni, Maria L Stewart, Michael J Keenan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular nutrition & food research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Diana B CoulonSchool of Nutrition and Food Science or Animal Sciences, Louisiana State University AgCenter, Baton Rouge, LA, 70803, USA.ORCID 0000-0002-5390-1051
Ryan PageSchool of Nutrition and Food Science or Animal Sciences, Louisiana State University AgCenter, Baton Rouge, LA, 70803, USA.ORCID 0000-0002-7538-4403
Anne M RaggioSchool of Nutrition and Food Science or Animal Sciences, Louisiana State University AgCenter, Baton Rouge, LA, 70803, USA.
Justin GuiceBIO-CAT, 9117 Three Notch Road, Troy, VA, 22974, USA.
Brain MarxExperimental Statistics, Louisiana State University, Baton Rouge, LA, 70803, USA.
Vishnupriya GourineniIngredion Incorporated, Bridgewater, NJ, 08807, USA.
Maria L StewartIngredion Incorporated, Bridgewater, NJ, 08807, USA.
Michael J KeenanSchool of Nutrition and Food Science or Animal Sciences, Louisiana State University AgCenter, Baton Rouge, LA, 70803, USA.ORCID 0000-0003-1282-8756

Funding

Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2005 to 2026
$26.5M
NIDDK NIH HHS P30 DK072476
6 · The paper itself

Abstract

scopeThe possible mechanisms of production of four novel resistant starch type 4 (RS4) products for total cecal fermentation in an in vivo rodent model are evaluated. METHODS AND

resultsForty weanling rats are randomly assigned to five groups (n = 8) for a 3-week study. Starches are the RS type 4 products, as 10% of weight of RS diets (RSA-RSD), and AMIOCA starch (100% amylopectin) comprises 53.6% weight of control (CON) and 43.6% weight of RS diets. The RS products vary by percent purity and origin (potato, corn, tapioca). At euthanasia, cecal contents, serum, GI tract, and abdominal fat are collected. RSB, RSC, and RSD fed rats have greater empty cecum weights, lower cecal content pH, higher cecal content wet weight, and higher total cecal content acetate and propionate than the CON and RSA fed rats. Two other indicators of fermentation, total cecal contents butyrate and glucagon-like peptide 1, do not have significant ANOVA F values, which require more subjects for 80% power.

conclusionRS4 products that are produced from different starch origins with varying amounts of RS4 content and different methods of production are not uniformly fermented in an in vivo model.

Indexed as

Abdominal FatAnimalsCecumDigestionGlucagon-Like Peptide 1MaleManihotPropionatesRats, Sprague-DawleySolanum tuberosumStarchZea maysGlucagon-Like Peptide 1PropionatesStarchfermentationglucagon-like peptide 1resistant starchresistant starch type 4short-chain fatty acids

Identifiers

PMID31789479
PMCPMC7092686

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.