SynthesisAmerican journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists2019
Effect of medication reconciliation interventions on outcomes: A systematic overview of systematic reviews.
Synthesis in American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Medication Management Strategies at Hospital Admission: A Systematic Review and Meta-Analysis.Clinical and translational science · 2026Pooled it
- Reducing medication errors for adults in hospital settings.The Cochrane database of systematic reviews · 2021Pooled it
- Pharmacist-Led Discharge Care to Reduce Postdischarge Health Care Utilization: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Trial
- Effect of Medication Reconciliation at Hospital Admission on 30-Day Returns to Hospital: A Randomized Clinical Trial.JAMA network open · 2021Trial
- Nurses' perspectives on obtaining best possible medication histories in a virtual care setting: a qualitative study.BMC health services research · 2026Article
- Multimorbidity, polypharmacy and frailty in critically ill older adults.European geriatric medicine · 2026Review
- Analytical approaches for medication management for patient safety: a scoping review.npj health systems · 2025Article
- Medication reconciliation and drug interactions in adult cystic fibrosis patients attending an outpatient clinic: A Cross-sectional study.Scientific reports · 2025Article
- ConciliaMed: an interactive mobile and web tool to reconcile chronic medications of patients undergoing elective surgery.BMJ health & care informatics · 2025Article
- A machine learning-based clinical predictive tool to identify patients at high risk of medication errors.Scientific reports · 2024Article
- Defining, identifying and addressing problematic polypharmacy within multimorbidity in primary care: a scoping review.BMJ open · 2024Article
- Development of a Discharge Counseling and Medication Reconciliation Process for Pediatric Patients Within a Large, Academic Health System.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- Medication reconciliationEuropean journal of hospital pharmacy : science and practice · 2023Article
- Participatory research to improve medication reconciliation for older adults in the community.Journal of the American Geriatrics Society · 2023Article
- Article
- Recommendations for outcome measurement for deprescribing intervention studies.Journal of the American Geriatrics Society · 2022Review
- Pharmacist-led medication reconciliation at patient discharge: a tool to reduce healthcare utilization? an observational study in patients 65 years or older.BMC geriatrics · 2022Observational
- Tools and tactics for postdischarge medication management interventions.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2021Article
- A case of pharmacist-led care team interventions to maximize rural patient quality of life.Exploratory research in clinical and social pharmacy · 2021Article
Corrections and comments
- Commented on by
Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
Abstract
purposeTo evaluate and summarize published evidence from systematic reviews examining medication reconciliation.
methodsMEDLINE, the Cochrane Database of Systematic Reviews, and the Database of Abstracts of Reviews of Effects were searched for English-language systematic reviews published from January 2004 to March 2019. Reviewers independently extracted information and scored review quality using the Assessment of Multiple Systematic Reviews (AMSTAR) tool. For reviews with AMSTAR scores above 7, Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was applied to assess evidence quality, with evidence summarized and conclusions compared across reviews.
resultsEleven reviews met the inclusion criteria, 5 of which used meta-analytic pooling. Most systematic reviews included primary studies of comprehensive bundled interventions that featured medication reconciliation as a central component. Reviews largely focused on transitions into and out of hospital settings. Five reviews focused exclusively on pharmacist-led interventions. Of the 5 reviews that considered all types of medication discrepancies, 3 reviews found very low-quality evidence that interventions reduced medication discrepancies. Neither of the 2 reviews that examined clinically significant medication discrepancies found any intervention effect. Of the 5 reviews that examined healthcare utilization outcomes, only 1 found any intervention effect, and that finding was based on low- to very low-quality evidence. Four reviews considered clinical outcomes, but none found any intervention effect.
conclusionAn overview of systematic reviews of medication reconciliation interventions found 9 high-quality systematic reviews. A minority of those reviews' conclusions were consistent with medication reconciliation alone having a measurable impact, and such conclusions were almost all based on very low-quality evidence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.