Evidence map›Paper›PMID 31788709›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

Pharmacokinetic evaluation of [

Vasko Kramer, Carlos Juri, Patrick J Riss, Rossana Pruzzo, Cristian Soza-Ried, Jonathan Flores, Ana Hurtado, Frank Rösch, Pedro Chana-Cuevas, Horacio Amaral

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The role of neuroimaging in Parkinson's disease.Journal of neurochemistry · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Vasko KramerCenter for Nuclear Medicine & PET/CT Positronmed, Julio Prado 714, Santiago, Chile. vkramer@positronpharma.cl.ORCID 0000-0002-5285-6447
Carlos JuriDepartment of Neurology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Patrick J RissDepartment of Chemistry, University of Oslo, Oslo, Norway.
Rossana PruzzoCenter for Nuclear Medicine & PET/CT Positronmed, Julio Prado 714, Santiago, Chile.
Cristian Soza-RiedCenter for Nuclear Medicine & PET/CT Positronmed, Julio Prado 714, Santiago, Chile.
Jonathan FloresCenter for Nuclear Medicine & PET/CT Positronmed, Julio Prado 714, Santiago, Chile.
Ana HurtadoCenter for Nuclear Medicine & PET/CT Positronmed, Julio Prado 714, Santiago, Chile.
Frank RöschInstitute of Nuclear Chemistry, Johannes Gutenberg-University, Mainz, Germany.
Pedro Chana-CuevasCentro de Trastornos del Movimiento, Santiago, Chile.
Horacio AmaralCenter for Nuclear Medicine & PET/CT Positronmed, Julio Prado 714, Santiago, Chile.
Itron (United States) · USJohannes Gutenberg University Mainz · DEPontificia Universidad Católica de Chile · CLUniversidad de Santiago de Chile · CLUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDopamine transporters (DAT) modulate pre-synaptic dopamine and physiological functions such as movement and reward. DAT also mirrors disease state in neurological disorders, rendering it an essential diagnostic target. [

methodsThirty-two healthy subjects underwent T1-weighted MRI and dynamic PET scans for 180 min with arterial blood sampling (n = 5) or 90 min without blood sampling (n = 25) after injection of 197.6 ± 12.2 MBq [

results[

conclusions[

Indexed as

DopaminePositron Emission Tomography Computed TomographyBrainDopamine Plasma Membrane Transport ProteinsHumansPositron-Emission TomographyReproducibility of ResultsDopamineDopamine Plasma Membrane Transport Proteins[18F]PR04.MZDopamine transporterParkinson’s diseasePET/CTPharmacokinetics

Identifiers

PMID31788709
OpenAlexW2989937127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.