Evidence map›Paper›PMID 31788624›Full record

ArticleACS omega2019

Unique Structural Features of Mule Deer Prion Protein Provide Insights into Chronic Wasting Disease.

Urška Slapšak, Giulia Salzano, Gregor Ilc, Gabriele Giachin, Jifeng Bian, Glenn Telling, Giuseppe Legname, Janez Plavec

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Urška SlapšakSlovenian NMR Centre, National Institute of Chemistry, SI-1000 Ljubljana, Ljubljana, Slovenia.
Giulia SalzanoLaboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, I-34136 Trieste, Trieste, Italy.
Gregor IlcSlovenian NMR Centre, National Institute of Chemistry, SI-1000 Ljubljana, Ljubljana, Slovenia.
Gabriele GiachinLaboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, I-34136 Trieste, Trieste, Italy.
Jifeng BianPrion Research Center (PRC) and Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80525, United States.
Glenn TellingPrion Research Center (PRC) and Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80525, United States.
Giuseppe LegnameLaboratory of Prion Biology, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, I-34136 Trieste, Trieste, Italy.
Janez PlavecSlovenian NMR Centre, National Institute of Chemistry, SI-1000 Ljubljana, Ljubljana, Slovenia.
Scuola Internazionale Superiore di Studi Avanzati · ITColorado State University · USEN-FIST Centre of Excellence (Slovenia) · SINational Institute of Chemistry · SIUniversity of Ljubljana · SI

Funding

Zoonotic potential of CWD and influence of environmental contamination on prion propagationP01AI077774 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI EDWARD Arthur HOOVER · 2008 to 2026
$36.1M
Characterizing the strain and host range properties of prions causing emergent forms of chronic wasting diseaseR01NS109376 · NINDS · COLORADO STATE UNIVERSITY · PI TELLING, GLENN C · 2018 to 2022
$2.4M
NIAID NIH HHS P01 AI077774NINDS NIH HHS R01 NS109376
6 · The paper itself

Abstract

Chronic wasting disease (CWD) is a highly infectious prion disease of cervids. Accumulation of prions, the disease-specific structural conformers of the cellular prion protein (PrP

Identifiers

PMID31788624
PMCPMC6882122
OpenAlexW2985020477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.