ArticleACS omega2019
Antibacterial PMMA Composite Cements with Tunable Thermal and Mechanical Properties.
Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Novel Antimicrobial Composites Modified with Nanosilver, CuSOMaterials (Basel, Switzerland) · 2026Article
- Antibiofilm Activity of a Novel Calcium Phosphate Cement Doped with Two Antibiotics.Journal of functional biomaterials · 2025Article
- Article
- The Effect of Incorporating Dimethylaminohexadecyl Methacrylate and/or 2-Methacryloyloxyethyl Phosphorylcholine on Flexural Strength and Surface Hardness of Heat Polymerized and 3D-Printed Denture Base Materials.Materials (Basel, Switzerland) · 2024Article
- Mechanical Properties and Liquid Absorption of Calcium Phosphate Composite Cements.Materials (Basel, Switzerland) · 2023Article
- Advances in materials used for minimally invasive treatment of vertebral compression fractures.Frontiers in bioengineering and biotechnology · 2023Review
- Different Modification Methods of Poly Methyl Methacrylate (PMMA) Bone Cement for Orthopedic Surgery Applications.The archives of bone and joint surgery · 2023Review
- Effect of the Antimicrobial Agents Peppermint Essential Oil and Silver Nanoparticles on Bone Cement Properties.Biomimetics (Basel, Switzerland) · 2022Article
- Development of Synthesis and Application of High Molecular Weight Poly(Methyl Methacrylate).Polymers · 2022Review
- Current approaches for the exploration of antimicrobial activities of nanoparticles.Science and technology of advanced materials · 2021Review
- Oxo-Titanium(IV) Complex/Polymer Composites-Synthesis, Spectroscopic Characterization and Antimicrobial Activity Test.International journal of molecular sciences · 2020Article
- The Role of Chitosan and Graphene Oxide in Bioactive and Antibacterial Properties of Acrylic Bone Cements.Biomolecules · 2020Review
- Acrylic Bone Cement Incorporated with Low Chitosan Loadings.Polymers · 2020Article
- Nile Red-Poly(Methyl Methacrylate)/Silica Nanocomposite Particles Increase the Sensitivity of Cervical Cancer Cells to Tamoxifen.Polymers · 2020Article
- Evaluation of Antibacterial and Cytotoxicity Properties of Silver Nanowires and Their Composites with Carbon Nanotubes for Biomedical Applications.International journal of molecular sciences · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PMMA-based cements are the most used bone cements in vertebroplasty and total hip arthroplasty. However, they present several drawbacks, including susceptibility to bacterial infection, monomer leakage toxicity, and high polymerization temperature, which can all lead to damage to the surrounding tissues and their failure. In the present study, silver nanowires (AgNWs) have been introduced to bestow antibacterial properties; chitosan (CS) to promote porosity and to reduce the polymerization temperature, without negatively affecting the mechanical performance; and methacryloyl chitosan (CSMCC) to promote cross-linking with methyl methacrylate (MMA) and reduce the quantity of monomer required for polymerization. Novel PMMA cements were formulated containing AgNWs (0 and 1% w/w) and CS or CSMCC at various concentrations (0, 10, 20, and 30% w/w), testing two different ratios of powder and MMA (P/L). Mechanical, thermal, antibacterial, and cytotoxic properties of the resulting composite cements were tested. Cements with concentrations of CS > 10% presented a significantly reduced polymerization temperature. The mechanical performances were affected for concentrations > 20% with a P/L concentration equal to 2:1. Concentrations of AgNWs as low as 1% w/w conferred antimicrobial activity against
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Registered trials
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