Evidence map›Paper›PMID 31788556›Full record

ArticleStigma and health2019

Trajectories of HIV-related internalized stigma and disclosure concerns among ART initiators and non-initiators in South Africa.

Brian T Chan, Brendan G Maughan-Brown, Laura M Bogart, Valerie A Earnshaw, Gugulethu Tshabalala, Ingrid Courtney, Janan J Dietrich, Catherine Orrell, Glenda E Gray, David R Bangsberg and 2 more

Abstract read
In one paragraph

Article in Stigma and health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
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  9. Integrating time into stigma and health research.Nature reviews psychology · 2022
    Review
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  13. Observational
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Brian T ChanDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Brendan G Maughan-BrownSouthern Africa Labour and Development Research Unit, University of Cape Town, Rondebosch, Cape Town, 7701, South Africa.
Laura M BogartHealth Unit, RAND Corporation, Santa Monica, CA, USA.
Valerie A EarnshawDepartment of Human Development and Family Sciences, University of Delaware, Newark, DE, USA.
Gugulethu TshabalalaPerinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Ingrid CourtneyDesmond Tutu HIV Foundation, University of Cape Town Medical School, Cape Town, South Africa.
Janan J DietrichPerinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Catherine OrrellDesmond Tutu HIV Foundation, University of Cape Town Medical School, Cape Town, South Africa.
Glenda E GrayPerinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
David R BangsbergOregon Health & Science University-Portland State University School of Public Health, Portland, Oregon, United States of America.
Alexander C TsaiHarvard Medical School, Boston, MA, USA.
Ingrid T KatzDepartment of Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
HIV Treatment Refusal Among Adults Presenting for Testing in Soweto, South AfricaK23MH097667 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI KATZ, INGRID T. · 2012 to 2016
$922k
Syndemics and Loss From the HIV Care Continuum in IndiaK23MH110338 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAN, BRIAN TAN · 2017 to 2020
$783k
Understanding and Addressing Disclosure to Members of Social Networks among People Recovering from Substance Use DisordersK01DA042881 · NIDA · UNIVERSITY OF DELAWARE · PI EARNSHAW, VALERIE ANN · 2017 to 2020
$756k
NIDA NIH HHS K01 DA042881NIMH NIH HHS K23 MH097667NIMH NIH HHS K23 MH110338NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

backgroundHIV-related stigma among people living with HIV (PLHIV) is associated with worse health outcomes. We used longitudinal data from a multi-site cohort in South Africa to assess changes over time in stigma after HIV diagnosis and determine whether antiretroviral therapy (ART) initiation is associated with stigma reduction.

methodsWe administered the Internalized AIDS-Related Stigma Scale (IARSS, a six-item dichotomous scale questionnaire) at baseline, three months, and six months to newly diagnosed ART-eligible participants between 2014-2015. A confirmatory factor analysis indicated that the IARSS contained a four-item internalized stigma factor (α=0.80) and a two-item disclosure concerns factor (α=0.75). We fitted multiple logistic regression models specifying internalized stigma/disclosure concerns at six months as the outcome and ART initiation as the predictor of interest.

resultsOf the 500 participants (187 men and 313 women) enrolled, 308 (62%) initiated ART. Internalized stigma declined among people entering care (mean score, 1.0 to 0.7, p<0.01); however, disclosure concerns remained unchanged (percentage endorsing either disclosure concern item, 78% to 77%, p=0.23). These findings were similar between ART initiators and non-initiators. We estimated a statistically significant positive association between ART initiation and disclosure concerns at six months (OR=1.88; 95% CI, 1.20-2.94) but not between ART initiation and internalized stigma at six months (OR=1.15; 95% CI, 0.75-1.78).

conclusionsAmong ART-eligible South African PLHIV entering into HIV care, internalized stigma modestly declined over time but disclosure concerns persisted. PLHIV who initiated ART were more likely to have persistent disclosure concerns over time as compared with those who did not start ART.

Indexed as

anticipated stigmadisclosureinternalized stigmaSouth AfricaStigma

Identifiers

PMID31788556
PMCPMC6884335

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.