Evidence map›Paper›PMID 31788537›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2019

Alzheimer's disease pathology explains association between dementia with Lewy bodies and APOE-ε4/TOMM40 long poly-T repeat allele variants.

Inga Prokopenko, Gentaro Miyakawa, Bang Zheng, Jani Heikkinen, Daniela Petrova Quayle, Chinedu Udeh-Momoh, Annique Claringbould, Juliane Neumann, Hazal Haytural, Marika A Kaakinen and 13 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Lack of epistatic interaction ofBrain communications · 2025
    Article
  3. Article
  4. Article
  5. Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  6. Article
  7. Frontiers in neurology · 2021
    Article
  8. Review
  9. Review
  10. ApoE Lipidation as a Therapeutic Target in Alzheimer's Disease.International journal of molecular sciences · 2020
    Review
  11. Review
  12. The Genetics of Alzheimer's Disease in the Chinese Population.International journal of molecular sciences · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 9 institutions in 4 countries.

Inga ProkopenkoSection of Genomics of Common Disease, Department of Medicine, Imperial College London, London, UK.
Gentaro MiyakawaGenetic and Molecular Epidemiology Group, Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), University of Lübeck, Lübeck, Germany.
Bang ZhengNeuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, London, UK.
Jani HeikkinenSection of Genomics of Common Disease, Department of Medicine, Imperial College London, London, UK.
Daniela Petrova QuayleNeuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, London, UK.
Chinedu Udeh-MomohNeuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, London, UK.
Annique ClaringbouldDepartment of Genetics, University Medical Centre Groningen, Groningen, The Netherlands.
Juliane NeumannNuffield Department of Clinical Neuroscience, Neuropathology and Oxford Parkinson's Disease Centre, University of Oxford, Oxford, UK.
Hazal HayturalNuffield Department of Clinical Neuroscience, Neuropathology and Oxford Parkinson's Disease Centre, University of Oxford, Oxford, UK.
Marika A KaakinenSection of Genomics of Common Disease, Department of Medicine, Imperial College London, London, UK.
Elena LoizidouSection of Genomics of Common Disease, Department of Medicine, Imperial College London, London, UK.
Esther MeissnerMax Planck Institute for Molecular Genetics, Berlin, Germany.
Lars BertramNeuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, London, UK.
BIOS consortium
Djordje O GvericMultiple Sclerosis and Parkinson's Tissue Bank, Imperial College London, London, UK.
Steve M GentlemanNeuropathology Unit, Department of Medicine, Imperial College London, London, UK.
Johannes AttemsInstitute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.
Robert PerneczkyNeuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, London, UK.
Thomas ArzbergerDepartment of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität München, Munich, Germany.
Pierandrea MugliaNeuroscience Discovery Medicine, UCB Pharma, Brussels Area, Belgium.
Christina M LillGenetic and Molecular Epidemiology Group, Lübeck Interdisciplinary Platform for Genome Analytics (LIGA), University of Lübeck, Lübeck, Germany.
Laura ParkkinenNuffield Department of Clinical Neuroscience, Neuropathology and Oxford Parkinson's Disease Centre, University of Oxford, Oxford, UK.
Lefkos T MiddletonNeuroepidemiology and Ageing Research Unit, School of Public Health, Imperial College London, London, UK.
Imperial College London · GBGenomics England · GBLudwig-Maximilians-Universität München · DEMax Planck Institute for Molecular Genetics · DEUniversity of Oxford · GBNewcastle University · GBScience Oxford · GBUCB Pharma (Belgium) · BEUniversity Medical Center Groningen · NL

Funding

Medical Research Council G0400074Medical Research Council G1100540Medical Research Council MR/L022656/1Parkinson's UK J-0901Wellcome Trust
6 · The paper itself

Abstract

introductionThe role of

methodsWe dissected genetic profiles within the

resultsDISCUSSION:

Indexed as

Alzheimer's diseaseAPOEApolipoprotein EAssociation analysisBrain banksDementia with Lewy bodiesLewy body dementiasNeuropathologyParkinson's diseaseParkinson's disease dementiaTOMM40

Identifiers

PMID31788537
PMCPMC6880091
OpenAlexW2990382736

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.