ArticleJournal of pharmaceutical health care and sciences2019
Risk factor analysis of the decrease in gait speed among Japanese older outpatients with polypharmacy.
Article in Journal of pharmaceutical health care and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Mechanistic Pathways Linking Type 2 Diabetes Mellitus, Hypertension, and Osteoarthritis to Falls in Older Adults: A Scoping Review.Healthcare (Basel, Switzerland) · 2026Review
- Potentially inappropriate medications are negatively associated with functional recovery in patients with sarcopenia after stroke.Aging clinical and experimental research · 2022Article
- Impaired Stabilization of Orthostatic Cerebral Oxygenation Is Associated With Slower Gait Speed: Evidence From The Irish Longitudinal Study on Ageing.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Article
- Relevance of Sociodemographics and Clinical Tests in Single- and Dual-Task Conditions as Gait Speed Predictors of Parkinson's Disease.Journal of clinical medicine · 2022Article
- Association between Kihon check list score and geriatric depression among older adults from ORANGE registry.PloS one · 2021Observational
- Using INTERCheckDrugs - real world outcomes · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBoth polypharmacy and frailty are critical issues faced by the elderly. The decrease in gait speed is an index of frailty, and it is generally associated with falls and fractures, which are risk factors requiring the need for support or long-term patient care. In this study, we assess the risk factors responsible for the decrease in gait speed in older outpatients with polypharmacy.
methodsThirty-one persons (13 men, 18 women) aged 65 years or above and regularly taking 5 or more internal medications participated in this study.
resultsPropensity score-adjusted multivariate logistic analysis showed that only number of medications was associated with the risk of decreasing gait speed (odds ratio: 16.00, 95% confidence interval:1.72-149.00,
conclusionThese results suggest that not only the number of medications but also the prescription contents is a risk factor for decrease in gait speed and may serve as indexes to identify patients at high risk of requiring support or long-term care.
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