Evidence map›Paper›PMID 31787979›Full record

ArticleFrontiers in immunology2019

Copper Regulates the Susceptibility of Zebrafish Larvae to Inflammatory Stimuli by Controlling Neutrophil/Macrophage Survival.

MingYue Chen, Yi Luo, JiangPing Xu, Ming-Xian Chang, Jing-Xia Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
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  7. CoSRSC advances · 2024
    Article
  8. Article
  9. Article
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  11. Veterinary world · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. The impact of metal availability on immune function during infection.Trends in endocrinology and metabolism: TEM · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

MingYue ChenKey Laboratory of Freshwater Animal Breeding, Ministry of Agriculture, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Yi LuoKey Laboratory of Freshwater Animal Breeding, Ministry of Agriculture, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
JiangPing XuKey Laboratory of Freshwater Animal Breeding, Ministry of Agriculture, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Ming-Xian ChangState Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Jing-Xia LiuKey Laboratory of Freshwater Animal Breeding, Ministry of Agriculture, College of Fisheries, Huazhong Agricultural University, Wuhan, China.
Huazhong Agricultural University · CNInstitute of Hydrobiology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Copper has been revealed to negatively affect the hematopoietic system, which has an important function in immune pathogen defense, but little is known about the potential mechanism. In this study, copper-stressed larvae exhibited significantly increased mortality as well as reduced percentages of GFP-labeled macrophages and neutrophils after

Indexed as

Aeromonas hydrophilaAnimalsAnimals, Genetically ModifiedApoptosisCell SurvivalCopperGram-Negative Bacterial InfectionsHost Microbial InteractionsInflammationLarvaMacrophagesNeutrophilsPhagocytosisReactive Oxygen SpeciesTranscriptomeZebrafishCopperReactive Oxygen Speciesapoptosiscopperimmune responsesmacrophages and neutrophilsmROSphagocytosis

Identifiers

PMID31787979
PMCPMC6856049
OpenAlexW2988195435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.