Evidence map›Paper›PMID 31787957›Full record

ArticleFrontiers in microbiology2019

Examination of the Glycine Betaine-Dependent Methylotrophic Methanogenesis Pathway: Insights Into Anaerobic Quaternary Amine Methylotrophy.

Adam J Creighbaum, Tomislav Ticak, Shrameeta Shinde, Xin Wang, Donald J Ferguson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Methionine synthesis and glycine betaine demethylation are intricately intertwined in cosmopolitan marine bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Methyl-Based Methanogenesis: an Ecological and Genomic Review.Microbiology and molecular biology reviews : MMBR · 2023
    Review
  6. Review
  7. Article
  8. Several ways one goal-methanogenesis from unconventional substrates.Applied microbiology and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adam J CreighbaumDepartment of Microbiology, Miami University, Oxford, OH, United States.
Tomislav TicakDepartment of Biological Sciences, University of Idaho, Moscow, ID, United States.
Shrameeta ShindeDepartment of Microbiology, Miami University, Oxford, OH, United States.
Xin WangDepartment of Microbiology, Miami University, Oxford, OH, United States.
Donald J FergusonDepartment of Microbiology, Miami University, Oxford, OH, United States.
Miami University · USUniversity of Idaho · US

Funding

Alternative routes of gut microbial methylamine metabolism that may limit trimethylamine N-oxide, a trigger for atherosclerosis.R01DK109345 · NIDDK · OHIO STATE UNIVERSITY · PI KRZYCKI, JOSEPH ADRIAN · 2016 to 2020
$2.2M
NIDDK NIH HHS R01 DK109345
6 · The paper itself

Abstract

Recent studies indicate that environmentally abundant quaternary amines (QAs) are a primary source for methanogenesis, yet the catabolic enzymes are unknown. We hypothesized that the methanogenic archaeon

Indexed as

COG5598glycine betainemethanogenesisone-carbonquaternary amine

Identifiers

PMID31787957
PMCPMC6855144
OpenAlexW2986863815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.