Evidence map›Paper›PMID 31787873›Full record

ArticleFrontiers in neuroscience2019

Neurons Expressing Pathological Tau Protein Trigger Dramatic Changes in Microglial Morphology and Dynamics.

Rahma Hassan-Abdi, Alexandre Brenet, Mohamed Bennis, Constantin Yanicostas, Nadia Soussi-Yanicostas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
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  4. Alzheimer's disease and gut-brain axis:Frontiers in neuroscience · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
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  11. Non-Rodent Genetic Animal Models for Studying Tauopathy: Review ofInternational journal of molecular sciences · 2021
    Review
  12. Zebrafish Models to Study New Pathways in Tauopathies.International journal of molecular sciences · 2021
    Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Rahma Hassan-AbdiINSERM, UMR1141, Hôpital Robert Debré, Paris, France.
Alexandre BrenetINSERM, UMR1141, Hôpital Robert Debré, Paris, France.
Mohamed BennisUniversité Cadi Ayyad, Marrakesh, Morocco.
Constantin YanicostasINSERM, UMR1141, Hôpital Robert Debré, Paris, France.
Nadia Soussi-YanicostasINSERM, UMR1141, Hôpital Robert Debré, Paris, France.
Cadi Ayyad University · MAHôpital Robert-Debré · FRInserm · FRNeuroDiderotUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microglial cells, the resident macrophages of the brain, are important players in the pathological process of numerous neurodegenerative disorders, including tauopathies, a heterogeneous class of diseases characterized by intraneuronal Tau aggregates. However, microglia response in Tau pathologies remains poorly understood. Here, we exploit a genetic zebrafish model of tauopathy, combined with live microglia imaging, to investigate the behavior of microglia

Indexed as

in vivo imagingmicrogliapro-inflammatory cytokinesTau hyperphosphorylationtauopathyTau proteinzebrafish

Identifiers

PMID31787873
PMCPMC6855094
OpenAlexW2986329520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.