ReviewThe obstetrician & gynaecologist : the journal for continuing professional development from the Royal College of Obstetricians & Gynaecologists2019
Fetal surgery for open spina bifida.
Review in The obstetrician & gynaecologist : the journal for continuing professional development from the Royal College of Obstetricians & Gynaecologists, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Myelomeningocele Surgery over the 10 Years Following the MOMS Trial: A Systematic Review of Outcomes in Prenatal versus Postnatal Surgical Repair.Medicina (Kaunas, Lithuania) · 2021Pooled it
- Preclinical stem cell therapy in fetuses with myelomeningocele: A systematic review and meta-analysis.Prenatal diagnosis · 2021Pooled it
- Anesthetic management and obstetric outcome for open fetal myelomeningocele repair at a Japanese center: a retrospective cohort study.BMC anesthesiology · 2026Article
- Advances in Fetal Repair of Spina Bifida Integrating Prenatal Surgery, Stem Cells, and Biomaterials.Biomedicines · 2026Review
- Anesthetic practices and physiological foundations in fetal surgery: a literature review.Einstein (Sao Paulo, Brazil) · 2026Review
- Role of urodynamics in predicting fecal incontinence in spina bifida and spinal cord injury patients.Pediatric surgery international · 2025Observational
- The Intrauterine Treatment of Open Spinal Dysraphism.Deutsches Arzteblatt international · 2025Review
- Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations.Stem cell research & therapy · 2024Article
- Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model.Tissue engineering and regenerative medicine · 2024Article
- Contemporary Outcomes of a National Fetal Spina Bifida Surgery Service.Prenatal diagnosis · 2024Article
- Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations.Research square · 2024Article
- Reflections upon the intrauterine repair of myelomeningocele.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Review
- International Consensus Statement on the Radiological Evaluation of Dysraphic Malformations of the Spine and Spinal Cord.AJNR. American journal of neuroradiology · 2024Review
- Longitudinal MRI in the context of in utero surgery for open spina bifida: A descriptive study.Acta obstetricia et gynecologica Scandinavica · 2024Article
- Myelomeningocele: Long-Term Neurosurgical Management.Advances and technical standards in neurosurgery · 2024Review
- Assessment of longitudinal brain development using super-resolution magnetic resonance imaging following fetal surgery for open spina bifida.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2023Article
- 2023 Canadian Urological Association/Pediatric Urologists of Canada guideline: Pediatric patients with neurogenic lower urinary tract dysfunction Full-text version.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023Article
- Implementation and Assessment of a Laparotomy-Assisted Three-Port Fetoscopic Spina Bifida Repair Program.Journal of clinical medicine · 2023Article
- Identifying predictive factors for bowel control in patients with spina bifida and spinal cord injuries.Pediatric surgery international · 2023Article
- Pre and postnatal care characteristics and management features of children born with myelomeningocele in the post-folate fortification era of staple foods in Costa Rica (2004-2022).Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
key contentSpina bifida is a congenital neurological condition with lifelong physical and mental effects.Open fetal repair of the spinal lesion has been shown to improve hindbrain herniation, ventriculoperitoneal shunting, independent mobility and bladder outcomes for the child and, despite an increased risk of prematurity, does not seem to increase the risk of neurodevelopmental impairment.Open fetal surgery is associated with maternal morbidity.Surgery at our institution is offered and performed according to internationally agreed criteria and protocols.Further evidence regarding long-term outcomes, fetoscopic repair and alternative techniques is awaited. LEARNING
objectivesTo understand the clinical effects, potential prevention and prenatal diagnosis of spina bifida.To understand the rationale and evidence supporting the benefits and risks of fetal repair of open spina bifida.To understand the criteria defining those who are likely to benefit from fetal surgery. ETHICAL ISSUES: The concept of the fetus as a patient, and issues surrounding fetal death or the need for resuscitation during fetal surgery.The associated maternal morbidity in a procedure performed solely for the benefit of the fetus/child.The financial implications of new surgical treatments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.