Evidence map›Paper›PMID 31787409›Full record

ArticleVaccine2020

Barriers to healthcare workers reporting adverse events following immunization in four regions of Ghana.

Jane F Gidudu, Anna Shaum, Alex Dodoo, Samuel Bosomprah, George Bonsu, Kwame Amponsa-Achiano, Delese M Darko, George Sabblah, Joseph Opare, Mawuli Nyaku and 6 more

Open access · greenAbstract read
In one paragraph

Article in Vaccine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
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  14. Information systems for vaccine safety surveillance.Human vaccines & immunotherapeutics · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Progress in Immunization Safety Monitoring - Worldwide, 2010-2019.MMWR. Morbidity and mortality weekly report · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Jane F GiduduCenter for Global Health, Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, United States. Electronic address: bwv5@cdc.gov.
Anna ShaumCenter for Global Health, Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, United States.
Alex DodooAfrican Collaborating Centre for Pharmacovigilance, Accra, Ghana.
Samuel BosomprahDepartment of Biostatistics, School of Public Health, University of Ghana, Accra, Ghana.
George BonsuDepartment of Disease Control and Prevention, Public Health Division, Ghana Health Service, Accra, Ghana.
Kwame Amponsa-AchianoDepartment of Disease Control and Prevention, Public Health Division, Ghana Health Service, Accra, Ghana.
Delese M DarkoGhana Food and Drugs Authority, Accra, Ghana.
George SabblahGhana Food and Drugs Authority, Accra, Ghana.
Joseph OpareAfrican Field Epidemiology Network, School of Public Health, University of Ghana, Accra, Ghana.
Mawuli NyakuCenter for Global Health, Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, United States.
Bernice Owusu-BoakyeAfrican Collaborating Centre for Pharmacovigilance, Accra, Ghana.
Abraham OduroNavrongo Health Research Centre, Health Research Division, Ghana Health Service, Navrongo, Ghana.
Raymond AborigoNavrongo Health Research Centre, Health Research Division, Ghana Health Service, Navrongo, Ghana.
Laura ConklinCenter for Global Health, Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, United States.
Paul WelagaNavrongo Health Research Centre, Health Research Division, Ghana Health Service, Navrongo, Ghana.
Hilda H AmpaduAfrican Collaborating Centre for Pharmacovigilance, Accra, Ghana.
Centers for Disease Control and Prevention · USNavrongo Health Research Centre · GHGhana Health Service · GHUniversity of Ghana · GH

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Despite didactic training on adverse events following immunization (AEFI) in Ghana, the reporting ratio of AEFI was 1.56 per 100,000 surviving infants in 2015, below the minimum reporting ratio of 10. We aimed to estimate the proportion of health care workers (HCWs) reporting AEFI and to identify barriers to reporting. We conducted a cross-sectional survey of HCWs in four regions in Ghana. A simple random sample of 176 health facilities was selected and up to two HCWs were randomly selected per facility. We used the Rao-Scott Chi-squared test to compare factors associated with reporting of AEFI in the last year. We used an open-ended question to identify reasons for low reporting. One supervisor from each facility, responsible for overall reporting and management of AEFI, was also interviewed. A total of 306 HCWs from 169 facilities were interviewed. Of these, 176 (57.5%) reported they had ever encountered an AEFI. Of the 120 who had encountered an AEFI in the last year, 66 (55.0%) indicated they had reported the AEFI, and 38 (31.7%) completed a reporting form. HCWs (n = 120) reported multiple barriers to reporting of AEFI; the most common barriers were fear of personal consequences (44.1%), lack of knowledge or training (25.2%), and not believing an AEFI was serious enough to report (22.2%). Discussion of AEFI during the last supervisory visit was significantly associated with reporting in the past year (OR 7.39; p < .001). Of 172 supervisors interviewed, 65 (37.8%) mentioned their facilties had ever encountered an AEFI; over 90% of facilities had reporting forms. We identified low reporting of AEFI and multiple barriers to reporting among HCWs in the four selected regions of Ghana. Discussing AEFI during supervisory visits with HCWs might improve reporting. Additionally, strategies to address fear of personal consequences as a barrier to reporting of AEFI are needed.

Indexed as

Adverse Drug Reaction Reporting SystemsHealth PersonnelMandatory ReportingCross-Sectional StudiesGhanaHumansImmunizationInfantAdverse events following immunizationBarriers to reportingFour regions in GhanaHealthcare workers

Identifiers

PMID31787409
PMCPMC10335122
OpenAlexW2990251318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.