Evidence map›Paper›PMID 31787209›Full record

ArticleBiophysical journal2020

Kinetic Mechanisms of Fast Glutamate Sensing by Fluorescent Protein Probes.

Catherine Coates, Silke Kerruth, Nordine Helassa, Katalin Török

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Catherine CoatesMolecular and Clinical Sciences Research Institute, St. George's University of London, London, United Kingdom.
Silke KerruthMolecular and Clinical Sciences Research Institute, St. George's University of London, London, United Kingdom.
Nordine HelassaMolecular and Clinical Sciences Research Institute, St. George's University of London, London, United Kingdom.
Katalin TörökMolecular and Clinical Sciences Research Institute, St. George's University of London, London, United Kingdom. Electronic address: ktorok@sgul.ac.uk.
St George's, University of London · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M02556X/1Biotechnology and Biological Sciences Research Council BB/S003894/1Wellcome TrustWellcome Trust 094385/Z/10/Z
6 · The paper itself

Abstract

We have developed probes based on the bacterial periplasmic glutamate/aspartate binding protein with either an endogenously fluorescent protein or a synthetic fluorophore as the indicator of glutamate binding for studying the kinetic mechanism of glutamate binding. iGluSnFR variants termed iGlu

Indexed as

Biosensing TechniquesGlutamic AcidKineticsLigandsLuminescent ProteinsModels, MolecularProtein ConformationGlutamic AcidLigandsLuminescent Proteins

Identifiers

PMID31787209
PMCPMC6950763
OpenAlexW2983563382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.