Evidence map›Paper›PMID 31787119›Full record

ArticlePublic health nutrition2020

Folic acid supplementation, dietary folate intake and risk of small for gestational age in China.

Huaqi Guo, Baohong Mao, Meng Wang, Qing Liu, Liping Yang, Yahui Xie, Yanxia Wang, Xiaochun He, Hongmei Cui, Xiaojuan Lin and 5 more

Open access · greenAbstract read
In one paragraph

Article in Public health nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Observational
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Huaqi GuoNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Baohong MaoNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Meng WangNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Qing LiuNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Liping YangGansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou, Gansu Province, People's Republic of China.
Yahui XieNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Yanxia WangNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Xiaochun HeNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Hongmei CuiNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Xiaojuan LinNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Ling LvNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Min ZhouNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Xiaoying XuNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Jie QiuNeonatology Department, Gansu Provincial Maternity and Child Care Hospital, 143 North Road, Qilihe District, Lanzhou730050, Gansu Province, People's Republic of China.
Yawei ZhangYale School of Public Health, 60 College Street, New Haven, CT06520, USA.
Gansu Provincial Maternal and Child Health Hospital · CNLanzhou University · CNGansu Provincial Hospital · CNYale University · US

Funding

Effects of Fine Particle Composition on Birth OutcomesR01ES019587 · NIEHS · YALE UNIVERSITY · PI BELL, MICHELLE L · 2011 to 2015
$2.6M
Air pollution and fetal growth in ChinaK02HD070324 · NICHD · YALE UNIVERSITY · PI ZHANG, YAWEI · 2011 to 2015
$582k
NICHD NIH HHS K02 HD070324NIEHS NIH HHS R01 ES019587
6 · The paper itself

Abstract

objectiveTo investigate the hypothesis that folic acid supplementation and dietary folate intake before conception and during pregnancy reduce the risk of small for gestational age (SGA) and to examine the joint effect of folic acid supplementation and dietary folate intake on the risk of SGA.

designParticipants were interviewed by trained study interviewers using a standardized and structured questionnaire. Information on birth outcomes and maternal complications was abstracted from medical records and dietary information was collected via a semi-quantitative FFQ before conception and during pregnancy.

settingA birth cohort data analysis using the 2010-2012 Gansu Provincial Maternity and Child Care Hospital.

participantsWomen (n 8758) and their children enrolled in the study.

resultsFolic acid supplementation was associated with a reduced risk of SGA (OR = 0·72, 95 % CI 0·60, 0·86), with the reduced risk seen mainly for SGA at ≥37 weeks of gestational age (OR = 0·70, 95 % CI 0·58, 0·85) and nulliparous SGA (OR = 0·67, 95 % CI 0·54, 0·84). There was no significant association between dietary folate intake and SGA risk.

conclusionsOur study suggested that folic acid supplementation was associated with a reduced risk of SGA and the risk varied by preterm status and parity.

Indexed as

Dietary SupplementsInfant, Small for Gestational AgeAdultChinaCohort StudiesFemaleFolic AcidHumansInfant, NewbornMaleMaternal Nutritional Physiological PhenomenaPreconception CarePregnancyPrenatal CareRisk FactorsYoung AdultFolic AcidCohort studyDietary folate intakeFolic acid supplementationSmall for gestational age

Identifiers

PMID31787119
PMCPMC10200399
OpenAlexW2994557457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.