ReviewThe American journal of psychiatry2019
Cortico-Limbic Interactions Mediate Adaptive and Maladaptive Responses Relevant to Psychopathology.
Review in The American journal of psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
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Who cites it
49 citing papers in PubMed.
- Posttraumatic stress disorder is associated with Alzheimer's disease-relevant molecular alterations in the basolateral amygdala of older Veterans.Neurobiology of aging · 2026Article
- Neuroanatomy reflects individual variability in impulsivity in youth.Molecular psychiatry · 2026Article
- Distinct associations between multimodal brain measures and psychopathology domains predict adolescent functioning.bioRxiv : the preprint server for biology · 2026Article
- Temporal Interference Electrical Stimulation for Neuropsychiatric Disorders: Mechanisms, Applications, and Translational Perspectives.International journal of molecular sciences · 2026Review
- Posttraumatic stress disorder is associated with Alzheimer's disease-relevant molecular remodeling in the amygdala of older Veterans.Research square · 2026Article
- Prefrontal Cortex Dysfunction as a Precipitating Factor for Schizophrenia and Depression.Journal of neurochemistry · 2026Review
- Emotional modulation of inhibitory control in rumination from empirical and computational perspectives.Cognitive, affective & behavioral neuroscience · 2026Article
- Impact of manganese and metal mixtures in blood, hair, and soil on child adaptive behaviors in Southeast Side Chicago.Environmental research · 2025Article
- Sex-Specific Effects of Early-Life Stress Exposure on Memory Performance and the Medial Prefrontal Cortex Transcriptomic Pattern in Adolescent Mice.Molecular neurobiology · 2025Article
- Role of Cav1.3 Channels in Brain-Heart Interactions: An Unexpected Journey.Biomedicines · 2025Review
- Exploring the Effect and Mechanism of Liraglutide in Treating Depression Based on Network Pharmacology and Experimental Analysis.Journal of cellular and molecular medicine · 2025Article
- Panic attack symptoms in patients with diabetic peripheral neuropathy.Comprehensive psychoneuroendocrinology · 2025Article
- Effects of pregnancy on neuron electrophysiology in prefrontal cortex, hippocampus, and basolateral amygdala of mouse brain.Animal models and experimental medicine · 2025Article
- Identifying neurobiological heterogeneity in clinical high-risk psychosis: a data-driven biotyping approach using resting-state functional connectivity.Schizophrenia (Heidelberg, Germany) · 2025Article
- Functional Brain Connectivity Predictors of Prospective Substance Use Initiation and Their Environmental Correlates.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Corticolimbic circuitry as a druggable target in schizophrenia spectrum disorders: a narrative review.Translational psychiatry · 2025Review
- Resting-state spontaneous brain activity as a neural marker for suicidal ideation in adolescents with non-suicidal self-injury: a voxel-wise and machine learning study.Frontiers in psychiatry · 2025Article
- Review
- Personalised transcranial magnetic stimulation for treatment-resistant depression, depression with comorbid anxiety and negative symptoms of schizophrenia: a narrative review.Singapore medical journal · 2024Review
- Socioeconomic resources in youth are linked to divergent patterns of network integration/segregation across the brain's transmodal axis.PNAS nexus · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Cortico-limbic circuits provide a substrate for adaptive behavioral and emotional responses. However, dysfunction of these circuits can result in maladaptive responses that are associated with psychopathology. The prefrontal-limbic pathways are of particular interest because they facilitate interactions among emotion, cognition, and decision-making functions, all of which are affected in psychiatric disorders. Regulatory aspects of the prefrontal cortex (PFC) are especially relevant to human psychopathology, as the PFC, in addition to its functions, is more recent from an evolutionary perspective and is considerably more complex in human and nonhuman primates compared with other species. This review provides a neuroanatomical and functional perspective of selected regions of the limbic system, the medial temporal lobe structures-the hippocampus and amygdala as well as regions of the PFC. Beyond the specific brain regions, emphasis is placed on the structure and function of critical PFC-limbic circuits, linking alterations in the processing of information across these pathways to the pathophysiology and psychopathology of various psychiatric illnesses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.