Evidence map›Paper›PMID 31786767›Full record

ArticleMolecular biology reports2020

Upregulation of the clpB gene in response to heat shock and beta-lactam antibiotics in Acinetobacter baumannii.

Waleska Yana Lazaretti, Elaine Luzia Dos Santos, José Luis da-Conceição Silva, Marina Kimiko Kadowaki, Rinaldo Ferreira Gandra, Alexandre Maller, Rita de Cássia Garcia Simão

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. The Role of ClpB in Bacterial Stress Responses and Virulence.Frontiers in molecular biosciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Waleska Yana LazarettiLaboratório de Bioquímica Molecular, Centro de Ciências Médicas e Farmacêuticas, Universidade Estadual do Oeste do Paraná, UNIOESTE, Rua Universitária, 2069, Cascavel, PR, 85814-110, Brazil.
Elaine Luzia Dos SantosLaboratório de Bioquímica Molecular, Centro de Ciências Médicas e Farmacêuticas, Universidade Estadual do Oeste do Paraná, UNIOESTE, Rua Universitária, 2069, Cascavel, PR, 85814-110, Brazil.
José Luis da-Conceição SilvaLaboratório de Bioquímica Molecular, Centro de Ciências Médicas e Farmacêuticas, Universidade Estadual do Oeste do Paraná, UNIOESTE, Rua Universitária, 2069, Cascavel, PR, 85814-110, Brazil.
Marina Kimiko KadowakiLaboratório de Bioquímica Molecular, Centro de Ciências Médicas e Farmacêuticas, Universidade Estadual do Oeste do Paraná, UNIOESTE, Rua Universitária, 2069, Cascavel, PR, 85814-110, Brazil.
Rinaldo Ferreira GandraLaboratório de Micologia Clínica, Hospital Universitário do Oeste do Paraná, Universidade Estadual do Oeste do Paraná, UNIOESTE, Cascavel, PR, Brazil.
Alexandre MallerLaboratório de Bioquímica Molecular, Centro de Ciências Médicas e Farmacêuticas, Universidade Estadual do Oeste do Paraná, UNIOESTE, Rua Universitária, 2069, Cascavel, PR, 85814-110, Brazil.
Rita de Cássia Garcia SimãoLaboratório de Bioquímica Molecular, Centro de Ciências Médicas e Farmacêuticas, Universidade Estadual do Oeste do Paraná, UNIOESTE, Rua Universitária, 2069, Cascavel, PR, 85814-110, Brazil. rita.simao@unioeste.br.ORCID http://orcid.org/0000-0003-2999-1218
Universidade Estadual do Oeste do Paraná · BR

Funding

CNPq fellow
6 · The paper itself

Abstract

The role of the clpB gene encoding HSP/chaperone ClpB was evaluated in the multiresistant antibiotic cells of Acinetobacter baumannii (RS4 strain) under stress-induced heat shock and different beta-lactams. The expression of the clpB gene was assessed by qPCR during heat shock at 45 °C and subinhibitory concentrations of ampicillin (30 μg mL

Indexed as

Genes, BacterialAcinetobacter baumanniiAnti-Bacterial AgentsBacterial Proteinsbeta-LactamsGene Expression Regulation, BacterialHeat-Shock ResponseUp-RegulationAnti-Bacterial AgentsBacterial Proteinsbeta-LactamsAntibioticsClpBHeat shock proteinsMultidrug resistanceStress response

Identifiers

PMID31786767
OpenAlexW2990315644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.