Evidence map›Paper›PMID 31786731›Full record

ArticleJournal of assisted reproduction and genetics2019

Discarding IVF embryos: reporting on global practices.

M Simopoulou, K Sfakianoudis, P Giannelou, A Rapani, E Maziotis, P Tsioulou, S Grigoriadis, E Simopoulos, D Mantas, M Lambropoulou and 3 more

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. When to create embryos or organoids for research.Journal of medical ethics · 2026
    Article
  3. The burnout: a silent saboteur in in vitro fertilization laboratories.Journal of assisted reproduction and genetics · 2025
    Review
  4. Article
  5. Article
  6. Too many embryos: a critical perspective on a global challenge.Journal of assisted reproduction and genetics · 2024
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

M SimopoulouDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, Mikras Asias, 11527, Athens, Greece. marasimopoulou@hotmail.com.ORCID https://orcid.org/0000-0002-1000-9100
K SfakianoudisCentre for Human Reproduction, Genesis Athens Clinic, Papanikoli, 15232, Athens, Greece.
P GiannelouDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, Mikras Asias, 11527, Athens, Greece.
A RapaniDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, Mikras Asias, 11527, Athens, Greece.
E MaziotisDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, Mikras Asias, 11527, Athens, Greece.
P TsioulouDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, Mikras Asias, 11527, Athens, Greece.
S GrigoriadisDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, Mikras Asias, 11527, Athens, Greece.
E SimopoulosDemocritus University of Thrace, Dragana, 68100, Alexandroupolis, Thrace, Greece.
D MantasConceive - The Gynecology Center, Dubai, United Arab Emirates.
M LambropoulouDemocritus University of Thrace, Dragana, 68100, Alexandroupolis, Thrace, Greece.
M KoutsilierisDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, Mikras Asias, 11527, Athens, Greece.
K PantosCentre for Human Reproduction, Genesis Athens Clinic, Papanikoli, 15232, Athens, Greece.
J C HarperReproductive Science Group, Institute for Women's Health, University College London, Gower Street, London, WC1E 6BT, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo provide a global scale report on a representative sample of the clinical embryology community depicting the practice of discarding supernumerary IVF embryos.

methodsA web-based questionnaire titled "Anonymous questionnaire on embryo disposal practices" was designed in order to ensure anonymous participation of practicing clinical embryologists around the world.

resultsDuring a data collection period of 8 months, 703 filled-in questionnaires from 65 countries were acquired. According to the data acquired, the majority of practitioners, dispose of embryos by placing them directly in a trash can strictly dedicated for embryo disposal for both fresh and frozen cycles (39% and 36.7% respectively). Moreover, 66.4% of practitioners discard the embryos separately-case by case-at different time points during the day. Over half of embryologists (54%) wait until day 6 to discard the surplus embryos, while 65.5% do not implement a specially allocated incubator space as a designated waiting area prior to disposal. The majority of 63.1% reported that this is a witnessed procedure. The vast majority of embryologists (93%) do not employ different protocols for different groups of patients. Nonetheless, 17.8% reported the request to perform a ceremony for these embryos. Assessing the embryologists' perspective, 59.5% of participants stated that the embryology practice would benefit from a universally accepted and practiced protocol. CONCLUSION(S): This study uniquely provides insight into global embryo disposal practices and trends. Results highlight the divergence between reported practices, while indicating the significance on standardization of practice, with embryologists acknowledging the need for a universally accepted protocol implementation.

Indexed as

Decision MakingEmbryo DispositionFertilization in VitroHumansReproductive Techniques, AssistedSurveys and QuestionnairesEmbryo disposal practicesIVFSurplus embryos

Identifiers

PMID31786731
PMCPMC6911130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.