Molecular characterization and expression patterns of two hormone-sensitive lipase genes in common carp Cyprinus carpio.

Xianhu Zheng, Hongyang Dang, Weihua Lv, Zhipeng Sun, Youyi Kuang, Dingchen Cao, Cuiyun Lu, Xiaowen Sun

Abstract read

In one paragraph

Article in Fish physiology and biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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0 citing papers in PubMed, 2 citations in OpenAlex.

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5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xianhu ZhengNational Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, No.43 Songfa Street, Daoli District, Harbin, 150070, Heilongjiang Province, China. zhengxianhu@hrfri.ac.cn.ORCID http://orcid.org/0000-0002-6206-8567

Hongyang DangNational Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, No.43 Songfa Street, Daoli District, Harbin, 150070, Heilongjiang Province, China.

Weihua LvNational Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, No.43 Songfa Street, Daoli District, Harbin, 150070, Heilongjiang Province, China.

Zhipeng SunNational Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, No.43 Songfa Street, Daoli District, Harbin, 150070, Heilongjiang Province, China.

Youyi KuangNational Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, No.43 Songfa Street, Daoli District, Harbin, 150070, Heilongjiang Province, China.

Dingchen CaoNational Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, No.43 Songfa Street, Daoli District, Harbin, 150070, Heilongjiang Province, China.

Cuiyun LuNational Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, No.43 Songfa Street, Daoli District, Harbin, 150070, Heilongjiang Province, China.

Xiaowen SunNational Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, No.43 Songfa Street, Daoli District, Harbin, 150070, Heilongjiang Province, China.

Chinese Academy of Fishery Sciences · CNMinistry of Agriculture and Rural Affairs · CN

Funding

National Natural Science Foundation of China (CN) 31302174the Central Public-interest Scientific Institution Basal Research Fund, HRFRI HSY201805M

6 · The paper itself

Abstract

The hormone-sensitive lipase (HSL) gene plays an important role in mammals' lipid metabolism. Therefore, its function in fish is capturing increasing attention. In this study, two distinct cDNAs, designated HSL1 and HSL2, are firstly identified from common carp Cyprinus carpio. The full-length cDNA of HSL1 and HSL2 consists of 3379 bp and 2732 bp, encoding polypeptide of 693 and 847 amino acids, respectively, and shares 60.6% amino acid identity. Phylogenetic analysis suggests that HSL1 and HSL2 are derived from paralogous genes, which might have arisen during a teleost-specific genome duplication event. The two HSL mRNAs are differentially expressed, both in terms of distribution among tissues and in terms of abundance during embryogenesis. Moreover, both HSL mRNAs are expressed in various tissues, the highest in abdominal fat. Meanwhile, the two HSLs are detected at all stages of embryonic development, suggesting that they could be functional and involved in embryogenesis. In addition, the results show that the mRNA expression level of HSL2 in the high group of intramuscular fat content is significantly higher than that in the low group (P < 0.01). The research provides basic data for developing a further understanding of the function of HSL as well as molecular regulation mechanism in fat metabolism of common carp.

Indexed as

AnimalsCarpsFish ProteinsLipaseSterol EsteraseFish ProteinsLipaseSterol EsteraseCyprinus carpioExpression patternHSL geneIntramuscular fat content

Identifiers

PMID31786726

DOI10.1007/s10695-019-00738-y

OpenAlexW2990172349

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.