Evidence map›Paper›PMID 31786694›Full record

ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2020

Clinical application of QuantiFERON-TB Gold in-tube in the diagnosis and treatment of tuberculosis.

Guangming Chen, Huabin Wang, Yanhong Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Guangming ChenDepartment of General Practice, Jinhua Municipal Central Hospital, Jinhua, People's Republic of China.
Huabin WangCentral Laboratory, Jinhua Municipal Central Hospital, Jinhua, People's Republic of China. whb798183844@126.com.ORCID http://orcid.org/0000-0002-9090-7380
Yanhong WangDepartment of Laboratory Medicine, Wenzhou Medical University, Wenzhou, People's Republic of China.
Jinhua Central Hospital · CNWenzhou Medical University · CN

Funding

Grant from Science Technology Department of Zhejiang province, China 2017C33206
6 · The paper itself

Abstract

At present, although it has made great progress in the diagnosis and treatment of tuberculosis, tuberculosis is still an important cause of morbidity and mortality. There were approximately 8.6 million new cases of tuberculosis in 2012, and approximately 1.3 million people died from tuberculosis. Early diagnosis and timely treatment are essential for controlling the spread of tuberculosis infection and reducing mortality. Conventional methods of Mycobacterium tuberculosis detection such as acid-fast staining microscopy and tuberculin skin test are widely used, but with low sensitivity or specificity. In recent years, a newly developed quantitative test, γ-interferon release test (IGRA), has been recognized and widely applied to the early diagnosis and monitoring of tuberculosis. QuantiFERON-TB Gold in-tube (QFT-GIT) is one of the mature IGRA methods. This paper summarizes the researches on QFT-GIT in recent years and introduces its principles, methodology, clinical application, and factors of uncertain results for the diagnosis and treatment of tuberculosis.

Indexed as

Interferon-gamma Release TestsHumansLatent TuberculosisMycobacterium tuberculosisReagent Kits, DiagnosticTuberculin TestTuberculosisReagent Kits, DiagnosticClinical applicationFalse negativeMycobacterium tuberculosis infectionQuantiFERON-TB Gold in-tubeUncertain results

Identifiers

PMID31786694
OpenAlexW2989720158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.