ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020
The impact of maternal epilepsy on delivery and neonatal outcomes.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Associations between epileptic seizures in pregnancy and adverse pregnancy outcomes: A systematic review and meta-analysis.PLoS medicine · 2025Pooled it
- Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child.The Cochrane database of systematic reviews · 2023Pooled it
- Review
- Pregnancy outcomes and changes to seizure frequency during pregnancy for patients with functional seizures.Epilepsy & behavior : E&B · 2025Article
- Examining the Joint Effects of Epilepsy and Mental Health Conditions on Severe Maternal Morbidity.Journal of women's health (2002) · 2025Article
- Neurological disorders in Pregnancy: Radiological insights and Obstetric implications.Pakistan journal of medical sciences · 2025Article
- The Effect of Seizures on Perinatal Outcomes in Pregnant Women with Epilepsy: A Single Center Retrospective Study.International journal of women's health · 2025Article
- The Rate of and Factors Associated with Delivery by Caesarean Section among Women with Epilepsy: Time Trend in a Single-Centre Cohort in Mazovia, Poland.Journal of clinical medicine · 2022Article
- Levetiracetam, lamotrigine and carbamazepine: which monotherapy during pregnancy?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- A nationwide analysis of maternal morbidity and acute postpartum readmissions in women with epilepsy.Epilepsy & behavior : E&B · 2021Article
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3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeEpilepsy is a common neurological disorder that may complicate reproductive health. Our aim in this study was to provide prospective ascertainment of obstetric and neonatal outcomes in women with epilepsy and investigate whether the risk of pregnancy, delivery, and neonatal complications differed between women with epilepsy and women without epilepsy.
methodsPregnant women with epilepsy and women without epilepsy (control group) were prospectively evaluated during the years 2013-2018. They were regularly followed by a neurologist and obstetrician until the end of pregnancy.
resultsDelivery and perinatal outcomes were compared between 112 women diagnosed with epilepsy and 277 women without epilepsy. Epilepsy was a significant risk factor for preterm delivery, cesarean section, fetal hypoxia, and Apgar score ≤ 7 at 5 min in offspring (odds ratio (OR) = 2.83, 95% confidence interval (CI) 1.03-7.76; OR = 5.61, 95% CI 3.44-9.14; OR = 1.81, 95% CI 1.08-3.04; OR = 8.12, 95% CI 4.04-16.35, respectively). Seizures during pregnancy had influence on the preference of cesarean section as a mode of delivery (ОR = 3.39; 95% CI 1.40-8.17). The rate of perinatal hypoxia was significantly higher in children born by cesarean section (ОR = 2.84; 95% CI 1.04-7.76). There was no significant difference between women with epilepsy and controls in malformation rate.
conclusionsWomen with epilepsy had an increased risk of pregnancy and delivery complications. Cesarean section was associated with an increased risk of complications in offspring.
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