Evidence map›Paper›PMID 31786626›Full record

SynthesisEuropean journal of nuclear medicine and molecular imaging2020

Molecular imaging of carotid artery atherosclerosis with PET: a systematic review.

Reza Piri, Oke Gerke, Poul F Høilund-Carlsen

Open access · greenAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Association of Atherosclerosis [Molecular imaging and biology · 2026
    Article
  4. [EJNMMI research · 2026
    Article
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  7. Review
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  11. Effective suppression of myocardial glucose uptake using predesigned low-carbohydrate boxed meals.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  12. Stroke and molecular imaging: a focus on FDG-PET.American journal of nuclear medicine and molecular imaging · 2023
    Review
  13. Review
  14. Review
  15. Longitudinal analysis of atherosclerotic plaques evolution: anJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Reza PiriDepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark. dr.reza.piri@gmail.com.ORCID 0000-0002-6379-3373
Oke GerkeDepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Poul F Høilund-CarlsenDepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
University of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo conduct a systematic review of articles on PET imaging of carotid atherosclerosis with emphasis on clinical usefulness and comparison with other imaging modalities.

methodsResearch articles reporting carotid artery PET imaging with different radiotracers until 30 November 2018 were systematically searched for in Medline/PubMed, Scopus, Embase, Google Scholar, and Cochrane Library. Duplicates were removed, and editorials, case studies, and investigations on feasibility or reproducibility of PET imaging and of patients with end-stage diseases or immunosuppressive medications were omitted. After quality assessment of included articles using Joanna Briggs Institute checklists, all eligible articles were reviewed.

resultsOf 1718 primary hits, 53 studies comprising 4472 patients, aged 47-91 years (78.8% males), were included and grouped under the following headlines: diagnostic performance, risk factors, laboratory findings, imaging modalities, and treatment.

conclusionFDG-PET visualizes the inflammatory part of carotid atherosclerosis enabling risk stratification to a certain degree, whereas NaF-PET seems to indicate long-term consequences of ongoing inflammation by demonstrating microcalcification allowing discrimination of atherosclerotic from normal arteries and suggesting clinically significant carotid atherosclerosis.

Indexed as

AtherosclerosisCarotid Artery DiseasesAgedAged, 80 and overCarotid ArteriesFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedMolecular ImagingPositron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsFluorodeoxyglucose F18Radiopharmaceuticals18F-fluorodeoxyglucose18F-sodium fluorideAtherosclerosisCarotid arteryInflammationPositron emission tomographySystematic review

Identifiers

PMID31786626
OpenAlexW2991377235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.