Evidence map›Paper›PMID 31786338›Full record

Trial reportJournal of psychosomatic research2020

An exploratory randomized sub-study of light-to-moderate intensity exercise on cognitive function, depression symptoms and inflammation in older adults with heart failure.

Laura S Redwine, Meredith A Pung, Kathleen Wilson, Katherine J Bangen, Lisa Delano-Wood, Barry Hurwitz

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of psychosomatic research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01625819 (Exploring Tai Chi as a Behavioral Intervention for Heart Failure Patients), which is not on this map. Cited by 27 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01625819 nacompletednot on this map

Exploring Tai Chi as a Behavioral Intervention for Heart Failure Patients

TypeinterventionalSponsorUniversity of California, San DiegoRan2010 to 2015Enrolled135ConditionsHeart FailureArmsTai Chi, Resistance Band, Health Education
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  6. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura S RedwineDepartment of Psychiatry, University of California, San Diego, CA, USA; College of Nursing, University of South Florida, Tampa, FL, USA. Electronic address: lredwine@usf.edu.
Meredith A PungDepartment of Family Medicine and Public Health, University of California, San Diego, CA, USA; College of Nursing, University of South Florida, Tampa, FL, USA.
Kathleen WilsonDepartment of Family Medicine and Public Health, University of California, San Diego, CA, USA.
Katherine J BangenDepartment of Psychiatry, University of California, San Diego, CA, USA.
Lisa Delano-WoodDepartment of Psychiatry, University of California, San Diego, CA, USA.
Barry HurwitzPsychology Department, University of Miami, USA.

Funding

Exploring Tai Chi as a Behavioral Intervention for Heart Failure PatientsR01HL096784 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI REDWINE, LAURA S · 2010 to 2013
$1.5M
NHLBI NIH HHS R01 HL096784
6 · The paper itself

Abstract

objectiveAlmost half of patients with heart failure (HF) have cognitive impairment. While exercise relates to better cognitive health, a hallmark of HF is exercise intolerance. The study objective was to explore whether light-to-moderate exercise improves cognitive function in patients with HF.

methodsThis was an exploratory parallel design study of 69 patients with symptomatic HF (mean age = 65, SD = 10), recruited from VA and University of California, San Diego Healthcare Systems. Participants were randomized to Tai Chi (TC) (n = 24), resistance band (RB) exercise (n = 22) or treatment as usual (TAU) (n = 23). The primary outcome was change in Montreal Cognitive Assessment (MoCA) scores. We further explored if changes in Beck Depression Inventory - IA (BDI-IA) scores or inflammation biomarkers, CRP, TNFα and IL-6 related to altered cognitive function.

resultsThere was a fixed effect of group for MoCA scores changes (F = 8.07, p = .001). TC and RB groups had greater MoCA score increases versus TAU, but no differences were found between TC and RB. Depression symptom changes predicted altered MoCA scores (ΔR

conclusionsLight-to-moderate exercises, TC and RB may improve cognitive function. However, the mechanisms remain unclear. ClinicalTrials.gov: NCT01625819.

Indexed as

AgedCognitionDepressionExerciseFemaleHeart FailureHumansInflammationMale

Identifiers

PMID31786338
PMCPMC7571258

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.