ArticleNeuron2020
Nested Neuronal Dynamics Orchestrate a Behavioral Hierarchy across Timescales.
Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.
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72 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The evolutionary trajectory of drosophilid walking.Current biology : CB · 2022Pooled it
- Aging-related behavioral defects in Caenorhabditis elegans.Biology open · 2026Article
- Neural sequences underlying directed turning in Caenorhabditis elegans.Nature neuroscience · 2026Article
- Optimization of connectome weights for a neural network model generating both forward and backward locomotion in C. elegans.Scientific reports · 2026Article
- Hungry for Knowledge: Octopamine Signaling Regulates Hunger-Enhanced Olfactory Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Atten-LTC-Enhanced MoE Model for Agent Trajectory Prediction in Autonomous Driving.Sensors (Basel, Switzerland) · 2026Article
- Short-term memory by distributed neural network oscillators in a simple nervous system.Current biology : CB · 2025Article
- Out of the single-neuron straitjacket: Neurons within assemblies change selectivity and their reconfiguration underlies dynamic coding.The Journal of physiology · 2025Article
- Dissection of Behavioral Components and the Role of Omega/Delta Turns for the Chemotaxis of C. elegans.Genes to cells : devoted to molecular & cellular mechanisms · 2025Article
- Embedding stochastic dynamics of the environment in spontaneous activity by prediction-based plasticity.eLife · 2025Article
- Symmetries and synchronization from whole-neural activity in theProceedings of the National Academy of Sciences of the United States of America · 2025Article
- The roles of feedback loops in the Caenorhabditis elegans rhythmic forward locomotion.PLoS computational biology · 2025Article
- A framework for analyzingbioRxiv : the preprint server for biology · 2025Article
- Hierarchical competing inhibition circuits govern motor stability in C. elegans.Nature communications · 2025Article
- The neurobiology of parenting and infant-evoked aggression.Physiological reviews · 2025Review
- The cost of language: functionally over-dominant language circuits in the human brain may limit cognitive abilities and non-verbal executive functions.Frontiers in human neuroscience · 2025Article
- Neuro-cognitive multilevel causal modeling: A framework that bridges the explanatory gap between neuronal activity and cognition.PLoS computational biology · 2024Article
- BIFROST: A method for registering diverse imaging datasets of theProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Hierarchical behavior control by a single class of interneurons.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Hand-Jaw Coordination as Mice Handle Food Is Organized around Intrinsic Structure-Function Relationships.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
12 more citing papers are in PubMed but not listed here.
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4 authors.
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Abstract
Classical and modern ethological studies suggest that animal behavior is organized hierarchically across timescales, such that longer-timescale behaviors are composed of specific shorter-timescale actions. Despite progress relating neuronal dynamics to single-timescale behavior, it remains unclear how different timescale dynamics interact to give rise to such higher-order behavioral organization. Here, we show, in the nematode Caenorhabditis elegans, that a behavioral hierarchy spanning three timescales is implemented by nested neuronal dynamics. At the uppermost hierarchical level, slow neuronal population dynamics spanning brain and motor periphery control two faster motor neuron oscillations, toggling them between different activity states and functional roles. At lower hierarchical levels, these faster oscillations are further nested in a manner that enables flexible behavioral control in an otherwise rigid hierarchical framework. Our findings establish nested neuronal activity patterns as a repeated dynamical motif of the C. elegans nervous system, which together implement a controllable hierarchical organization of behavior.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.