Evidence map›Paper›PMID 31785914›Full record

ArticleThe Science of the total environment2020

Human health risks due to airborne polychlorinated biphenyls are highest in New Bedford Harbor communities living closest to the harbor.

Wendy J Heiger-Bernays, Kathryn Scott Tomsho, Komal Basra, Zoe E Petropoulos, Kathryn Crawford, Andres Martinez, Keri C Hornbuckle, Madeleine K Scammell

Open access · hybridAbstract read
In one paragraph

Article in The Science of the total environment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Wendy J Heiger-BernaysBoston University School of Public Health, Department of Environmental Health, 715 Albany St., Talbot Building, Boston, MA 02118, United States. Electronic address: whb@bu.edu.
Kathryn Scott TomshoBoston University School of Public Health, Department of Environmental Health, 715 Albany St., Talbot Building, Boston, MA 02118, United States.
Komal BasraBoston University School of Public Health, Department of Environmental Health, 715 Albany St., Talbot Building, Boston, MA 02118, United States.
Zoe E PetropoulosBoston University School of Public Health, Department of Environmental Health, 715 Albany St., Talbot Building, Boston, MA 02118, United States.
Kathryn CrawfordBoston University School of Public Health, Department of Environmental Health, 715 Albany St., Talbot Building, Boston, MA 02118, United States.
Andres MartinezDepartment of Civil & Environmental Engineering, IIHR-Hydroscience and Engineering, 4105 Seamans Center for the Engineering Arts and Sciences, The University of Iowa, Iowa City, IA 52242, United States.
Keri C HornbuckleDepartment of Civil & Environmental Engineering, IIHR-Hydroscience and Engineering, 4105 Seamans Center for the Engineering Arts and Sciences, The University of Iowa, Iowa City, IA 52242, United States.
Madeleine K ScammellBoston University School of Public Health, Department of Environmental Health, 715 Albany St., Talbot Building, Boston, MA 02118, United States.
Boston University · USUniversity of Iowa · US

Funding

Training CoreP42ES013661 · NIEHS · UNIVERSITY OF IOWA · PI Rachel Frances Marek · 2006 to 2026
$60.3M
Training CoreP42ES007381 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SHERR, DAVID H · 1995 to 2019
$46.1M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
Environmental Epidemiology in Community SettingsT32ES014562 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Birgit Gunhild Claus Henn · 2006 to 2026
$7.7M
NIEHS NIH HHS P30 ES005605NIEHS NIH HHS P42 ES007381NIEHS NIH HHS P42 ES013661NIEHS NIH HHS T32 ES014562
6 · The paper itself

Abstract

In response to concerns raised by communities surrounding the New Bedford Harbor Superfund site, we completed a field and modeling study that concluded the harbor is the primary source of polychlorinated biphenyls (PCBs) in air around the harbor. The follow-up question from residents was whether the PCBs measured in air pose a risk to their health. The US Environmental Protection Agency focuses their site-specific, risk-based decisions for site clean-up on cancers. We focused our assessment on the non-cancer effects on the thyroid based on the congener specific patterns and concentrations of PCBs measured in air near and distant to the harbor. Human and animal studies of PCB-induced effects on the thyroid provide evidence to support our analysis. Drawing from the published toxicological data, we used a Margin of Exposure (MOE) approach to derive a human-equivalent concentration in air associated with human health effects on the thyroid. Based on the MOEs calculated herein, evaluation of the MOE indicates that changes in thyroid hormone levels are possible among people living adjacent to the Harbor. Changes in thyroid hormone levels are more likely among people who live near the harbor compared to residents living in areas distant from the harbor. This risk assessment documents potential health risks associated with proximity to a marine Superfund Site using site-specific ambient air PCB congener data.

Indexed as

AnimalsEnvironmental MonitoringHumansPolychlorinated BiphenylsRisk AssessmentPolychlorinated BiphenylsAmbient airMargin of ExposurePCB congenerPolychlorinated biphenylsSuperfundThyroid

Identifiers

PMID31785914
PMCPMC7015809
OpenAlexW2984398844

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.