SynthesisHernia : the journal of hernias and abdominal wall surgery2020
Seroma prevention strategies in laparoscopic ventral hernia repair: a systematic review.
Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 6 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- A Systematic Review and Meta-Analysis of Randomized Controlled Trials on Fascial Defect Closure Versus Bridged Repair in Laparoscopic Ventral Hernia Mesh Repair.World journal of surgery · 2026Pooled it
- Comparison of facial defect closure and non-fascial closure in ventral hernia repair: A systematic review and Meta-analysis of randomized controlled trials with trial sequential analysis.Hernia : the journal of hernias and abdominal wall surgery · 2026Pooled it
- Hybrid intraperitoneal onlay mesh repair for incisional hernias: a systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- Laparoscopic treatment of ventral hernias: the Italian national guidelines.Updates in surgery · 2023Guideline
- Fascial defect closure versus bridged repair in laparoscopic ventral hernia mesh repair: a systematic review and meta-analysis of randomized controlled trials.Hernia : the journal of hernias and abdominal wall surgery · 2022Pooled it
- Intraperitoneal versus extraperitoneal mesh in minimally invasive ventral hernia repair: a systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2022Pooled it
- Influence of internal ring defect closure on postoperative seroma formation after laparoscopic transabdominal preperitoneal repair for large indirect inguinal hernia: A randomized controlled study.Hernia : the journal of hernias and abdominal wall surgery · 2026Trial
- Hydrodissection in transabdominal preperitoneal repair for indirect inguinal hernia: A randomized controlled trial.Hernia : the journal of hernias and abdominal wall surgery · 2026Trial
- Recurrence rate and mesh bulging are reduced with primary fascial closure in ventral hernia repair: the PROSECO randomized clinical trial.The British journal of surgery · 2025Trial
- TACKoMesh - A randomised controlled trial comparing absorbable versus non-absorbable tack fixation in laparoscopic IPOM + repair of primary incisional hernia using post-operative pain and quality of life - Reliatack™ versus Protack™.Hernia : the journal of hernias and abdominal wall surgery · 2024Trial
- Laparoscopic ventral hernia repair: early follow-up of a randomized controlled study of primary fascial closure before mesh placement.The British journal of surgery · 2024Trial
- Using local hemostatic to prevent seromas in patients with large incisional hernias randomized controlled trial.Hernia : the journal of hernias and abdominal wall surgery · 2021Trial
- Long-term outcomes of a modified LIRA (laparoscopic intracorporeal rectus aponeuroplasty) technique for ventral hernia repair.Surgical endoscopy · 2026Article
- Post-operative seroma formation following laparoscopic inguinal hernia repair: a cross-sectional study.Annals of medicine and surgery (2012) · 2025Article
- Postoperative outcomes and wound events in incisional hernia repair using hybrid mesh: results from a prospective multicenter italian study.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Pitfalls and complications of enhanced-view totally extraperitoneal approach to abdominal wall reconstruction.Surgical endoscopy · 2023Review
- Peritoneal Bridging Versus Nonclosure in Laparoscopic Ventral Hernia Repair: A Randomized Controlled Trial.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2023Article
- Laparoscopic ventral and incisional hernia repair using intraperitoneal onlay mesh with peritoneal bridging.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- Are laparoscopic and open ventral hernia repairs truly comparable?: A propensity-matched study in large ventral hernias.Surgical endoscopy · 2021Article
- Robotic-assisted, laparoscopic, and open incisional hernia repair: early outcomes from the Prospective Hernia Study.Hernia : the journal of hernias and abdominal wall surgery · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic ventral hernia repair (LVHR) has been increasing in popularity over the years. Seroma formation is a common complication of LVHR. The aim of this study is to review the current evidence on seroma prevention strategies following LVHR.
methodsA systematic search of PubMed, Embase (1946-13 February 2019) and Medline (1946-13 February 2019) databases was conducted using terms which include "seroma", "hernia, ventral" and "laparoscopy". All studies are comparative retrospective or prospective human adult studies in peer-reviewed journals describing at least one intra-operative intervention designed to decrease the rate of seroma formation in laparoscopic ventral hernia repair.
resultsThe database searches identified 3762 citations, and 21 studies were included for final analysis. Five studies compared the different methods of mesh fixation, nine studies compared primary defect closure (PFC) and bridged repair, two studies compared the effect of different types of meshes, two studies looked into the use of electrical cauterization, one study compared single- site laparoscopy with conventional laparoscopy, one study looked into the use of fibrin sealant and one study compared transabdominal preperitoneal placement of mesh with conventional repair. PFC appears to be the most promising with large studies showing a low rate of seroma formation with additional benefits of decreasing wound infection and recurrence rate. Cauterisation of hernia sac and injection of fibrin sealant also show promising results but are mainly derived from small studies. Other strategies did not demonstrate benefit.
conclusionCurrently, primary fascial closure appears to be the most promising strategy available to decrease seroma formation after LVHR based on the results of large studies. Other promising strategies that decrease dead space such as cauterisation of the sac and fibrin sealant injection will require further multicentre trials to confirm benefit before an increase in operative time and cost can be justified for their routine use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.