ReviewJournal of neural transmission (Vienna, Austria : 1996)2020
Co-occurrence of pain syndromes.
Review in Journal of neural transmission (Vienna, Austria : 1996), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.
- Effect of physical activity and exercise on endometriosis-associated symptoms: a systematic review.BMC women's health · 2021Pooled it
- Impact of visceral pain on migraine symptoms in comorbid patients: a retrospective observational study.The journal of headache and pain · 2025Observational
- [Multiple comorbidities with migraine-Is there a common cause?]Schmerz (Berlin, Germany) · 2025Review
- Is there a relationship between symptoms and types of endometriosis according to #ENZIAN? A comparative study of preoperative questionnaires.Archives of gynecology and obstetrics · 2025Article
- Neuromodulation in Chronic Migraine: Evidence and Recommendations from the GRADE Framework.Advances in therapy · 2025Review
- Does BMI Have an Impact on Endometriosis Symptoms and Endometriosis Types According to the #ENZIAN Classification?Journal of clinical medicine · 2025Article
- Menopause, Perimenopause, and Migraine: Understanding the Intersections and Implications for Treatment.Neurology and therapy · 2025Review
- A network analysis of changing pain cooccurrence in older adults findings from the second wave of the COPERNICUS study.Scientific reports · 2025Article
- Validation of the Arabic Version of the Fibromyalgia Survey Questionnaire.Journal of pain research · 2025Article
- Adenomyosis in patients with rheumatic diseases: a cross-disciplinary clinical observation.Frontiers in reproductive health · 2025Article
- Pain from Internal Organs and Headache: The Challenge of Comorbidity.Diagnostics (Basel, Switzerland) · 2024Review
- Presenteeism and associated factors among women with menstrual symptoms.Archives of gynecology and obstetrics · 2024Article
- Health equity, care access and quality in headache - part 1.The journal of headache and pain · 2024Review
- Pelvic Pain of Myofascial Origin in Women: Correlation with Lower Urinary Tract Symptoms.Advances in urology · 2024Article
- Symptom tracking in endometriosis using digital technologies: Knowns, unknowns, and future prospects.Cell reports. Medicine · 2023Review
- Systematic review and meta-analysis of calculating degree of comorbidity of irritable bowel syndrome with migraine.BioPsychoSocial medicine · 2023Article
- Myofascial Pain Syndrome: A Nociceptive Condition Comorbid with Neuropathic or Nociplastic Pain.Life (Basel, Switzerland) · 2023Article
- Referred pain: characteristics, possible mechanisms, and clinical management.Frontiers in neurology · 2023Review
- A Comprehensive Treatment Protocol for Endometriosis Patients Decreases Pain and Improves Function.International journal of women's health · 2023Article
- Clinical profiling of specific diagnostic subgroups of women with chronic pelvic pain.Frontiers in reproductive health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many pain conditions in patients tend to co-occur, influencing the clinical expressions of each other in various ways. This paper summarizes the main concurrent pain conditions by analyzing the major interactions observed. In particular, co-occurrence will be examined in: visceral pain (especially ischemic heart disease, irritable bowel syndrome, dysmenorrhea/endometriosis and urinary pain), fibromyalgia, musculoskeletal pain and headache. Two concurrent visceral pains from internal organs sharing at least part of their central sensory projection can give rise to viscero-visceral hyperalgesia, i.e., enhancement of typical pain symptoms from both districts. Visceral pain, headache and musculoskeletal pains (myofascial pain from trigger points, joint pain) can enhance pain and hyperalgesia from fibromyalgia. Myofascial pain from trigger points can perpetuate pain symptoms from visceral pain conditions and trigger migraine attacks when located in the referred pain area from an internal organ or in cervico-facial areas, respectively. The pathophysiology of these pain associations is complex and probably multifactorial; among the possible processes underlying the mutual influence of symptoms recorded in the associations is modulation of central sensitization phenomena by nociceptive inputs from one or the other condition. A strong message in these pain syndrome co-occurrence is that effective treatment of one of the conditions can also improve symptoms from the other, thus suggesting a systematic and thorough evaluation of the pain patient for a global effective management of his/her suffering.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.