ArticleScientific reports2019
Age-related decrease in collagen proton fraction in tibial tendons estimated by magnetization transfer modeling of ultrashort echo time magnetic resonance imaging (UTE-MRI).
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
26 citing papers in PubMed, 38 citations in OpenAlex.
- Monitoring urinary collagen metabolite changes following collagen peptide ingestion and physical activity using ELISA with anti active collagen oligopeptide antibody.Scientific reports · 2021Trial
- Accelerated ultrashort echo time quantitative magnetization transfer (UTE-qMT) imaging of macromolecular fraction (MMF) in cortical bone based on a self-attention convolutional neural network.Magnetic resonance imaging · 2025Article
- Estimation of Trabecular Bone Volume with Dual-Echo Ultrashort Echo Time (UTE) Magnetic Resonance Imaging (MRI) Significantly Correlates with High-Resolution Computed Tomography (CT).Journal of imaging · 2025Article
- Significant age-related differences between lower leg muscles of older and younger female subjects detected by ultrashort echo time magnetization transfer modeling.NMR in biomedicine · 2024Article
- Ultrashort echo time MRI detects significantly lower collagen but higher pore water in the tibial cortex of female patients with osteopenia and osteoporosis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Article
- Fast dual-echo estimation of apparent long T2 fraction using ultrashort echo time magnetic resonance imaging in tibialis tendons and its osteoporosis-related differences in women.Quantitative imaging in medicine and surgery · 2024Article
- Ultrasound attenuation of cortical bone correlates with biomechanical, microstructural, and compositional properties.European radiology experimental · 2024Article
- Tendon evaluation with ultrashort Echo Time (UTE) MRI: A Systematic Review.Frontiers in musculoskeletal disorders · 2024Article
- Correlations between elastic modulus and ultrashort echo time (UTE) adiabatic T1ρ relaxation time (UTE-Adiab-T1ρ) in Achilles tendons and entheses.Journal of biomechanics · 2023Article
- Quantative MRI predicts tendon mechanical behavior, collagen composition, and organization.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Article
- Ultrashort echo time magnetization transfer imaging of knee cartilage and meniscus after long-distance running.European radiology · 2023Article
- Article
- Robust Assessment of Macromolecular Fraction (MMF) in Muscle with Differing Fat Fraction Using Ultrashort Echo Time (UTE) Magnetization Transfer Modeling with Measured T1.Diagnostics (Basel, Switzerland) · 2023Article
- MRI-based porosity index (PI) and suppression ratio (SR) in the tibial cortex show significant differences between normal, osteopenic, and osteoporotic female subjects.Frontiers in endocrinology · 2023Article
- Making the invisible visible-ultrashort echo time magnetic resonance imaging: Technical developments and applications.Applied physics reviews · 2022Review
- Correlation between the elastic modulus of anterior cruciate ligament (ACL) and quantitative ultrashort echo time (UTE) magnetic resonance imaging.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
- Preliminary study on the assessment of early cartilage degeneration by quantitative ultrashort echo time magnetic resonance imagingQuantitative imaging in medicine and surgery · 2022Article
- MRI-based mechanical competence assessment of bone using micro finite element analysis (micro-FEA): Review.Magnetic resonance imaging · 2022Review
- Lower Macromolecular Content in Tendons of Female Patients with Osteoporosis versus Patients with Osteopenia Detected by Ultrashort Echo Time (UTE) MRI.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Clinical magnetic resonance imaging (MRI) sequences are not often capable of directly visualizing tendons. Ultrashort echo time (UTE) MRI can acquire high signal from tendons thus enabling quantitative assessments. Magnetization transfer (MT) modeling combined with UTE-MRI-UTE-MT-modeling-can indirectly assess macromolecular protons in the tendon. This study aimed to determine if UTE-MT-modeling is a quantitative technique sensitive to the age-related changes of tendons. The legs of 26 young healthy (29 ± 6 years old) and 22 elderly (75 ± 8 years old) female subjects were imaged using UTE sequences on a 3T MRI scanner. Institutional review board approval was obtained, and all recruited subjects provided written informed consent. T1 and UTE-MT-modeling were performed on anterior tibialis tendons (ATT) and posterior tibialis tendons (PTT) as two representative human leg tendons. A series of MT pulse saturation powers (500-1500°) and frequency offsets (2-50 kHz) were used to measure the macromolecular fraction (MMF) and macromolecular T2 (T2
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Registered trials
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