Evidence map›Paper›PMID 31784617›Full record

ArticleScientific reports2019

Hyperventilation-induced heart rate response as a potential marker for cardiovascular disease.

Selwynne M Hawkins, Dominik P Guensch, Matthias G Friedrich, Giulia Vinco, Gobinath Nadeshalingham, Michel White, Francois-Pierre Mongeon, Elizabeth Hillier, Tiago Teixeira, Jacqueline A Flewitt and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Observational
  2. Abnormal coronary vascular response in patients with long COVID syndrome - a case-control study using oxygenation-sensitive cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Observational
  3. Article
  4. Article
  5. The reproducibility of breathing maneuvers as a vasoactive stimulus in the heart: an oxygenation-sensitive resonance imaging study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Selwynne M HawkinsResearch Institute of the McGill University Health Centre, Montreal, Canada.
Dominik P GuenschDepartment of Anaesthesiology and Pain Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.
Matthias G FriedrichDepartments of Medicine and Diagnostic Radiology, McGill University Health Centre, Montreal, Canada.
Giulia VincoDepartments of Medicine and Diagnostic Radiology, McGill University Health Centre, Montreal, Canada.
Gobinath NadeshalinghamPhilippa and Marvin Carsley CMR Center at the Montreal Heart Institute, Montreal, Canada.
Michel WhitePhilippa and Marvin Carsley CMR Center at the Montreal Heart Institute, Montreal, Canada.
Francois-Pierre MongeonPhilippa and Marvin Carsley CMR Center at the Montreal Heart Institute, Montreal, Canada.
Elizabeth HillierResearch Institute of the McGill University Health Centre, Montreal, Canada.
Tiago TeixeiraPhilippa and Marvin Carsley CMR Center at the Montreal Heart Institute, Montreal, Canada.
Jacqueline A FlewittStephenson Cardiovascular MR Centre, Libin Cardiovascular Institute of Alberta, Calgary, Canada.
Balthasar EberleDepartment of Anaesthesiology and Pain Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.
Kady FischerDepartment of Anaesthesiology and Pain Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland. kady.fischer@insel.ch.ORCID http://orcid.org/0000-0002-7765-4550
Montreal Heart Institute · CAUniversity of Bern · CHMcGill University Health Centre · CALibin Cardiovascular Institute of Alberta · CAUniversity of Calgary · CAUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increase of heart rate to physical or mental stress reflects the ability of the autonomous nervous system and the heart to respond adequately. Hyperventilation is a user-controlled breathing maneuver that has a significant impact on coronary function and hemodynamics. Thus, we aimed to investigate if the heart rate response to hyperventilation (HRR

Indexed as

Adrenergic beta-AntagonistsAdultBiomarkersCardiovascular DiseasesCase-Control StudiesFemaleHeart FailureHeart RateHumansHyperventilationMaleMiddle AgedSensitivity and SpecificityAdrenergic beta-AntagonistsBiomarkers

Identifiers

PMID31784617
PMCPMC6884614
OpenAlexW2990020467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.