ArticleNature communications2019
An interhemispheric neural circuit allowing binocular integration in the optic tectum.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- The tectal melanocortin system modulates energy-dependent visual avoidance behavior in zebrafish.iScience · 2026Article
- Neurotrophic Modulation Restores Motor and Developmental Defects in Zebrafish Models of ints11 Deficiency.Journal of neurochemistry · 2026Article
- Lrrn-mediated retinal ganglion cell targeting drives visual circuit assembly for brightness and contrast detection.Science advances · 2026Article
- Article
- How do fish miss? Attack strategies of threespine stickleback capturing non-evasive prey.The Journal of experimental biology · 2024Article
- Development of the Binocular Circuit.Annual review of neuroscience · 2024Review
- The adaptor protein 2 (AP2) complex modulates habituation and behavioral selection across multiple pathways and time windows.iScience · 2024Article
- Transcriptional control of visual neural circuit development by GS homeobox 1.PLoS genetics · 2024Article
- Bilateral Retinofugal Pathfinding Impairments Limit Behavioral Compensation in Near-Congenital One-EyedeNeuro · 2024Article
- Functional and pharmacological analyses of visual habituation learning in larval zebrafish.eLife · 2023Article
- Recurrent network interactions explain tectal response variability and experience-dependent behavior.eLife · 2023Article
- From perception to behavior: The neural circuits underlying prey hunting in larval zebrafish.Frontiers in neural circuits · 2023Review
- Dominant ARF3 variants disrupt Golgi integrity and cause a neurodevelopmental disorder recapitulated in zebrafish.Nature communications · 2022Article
- Input from torus longitudinalis drives binocularity and spatial summation in zebrafish optic tectum.BMC biology · 2022Article
- A cell-ECM mechanism for connecting the ipsilateral eye to the brain.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- The tectum/superior colliculus as the vertebrate solution for spatial sensory integration and action.Current biology : CB · 2021Review
- Article
- Bilateral visual projections exist in non-teleost bony fish and predate the emergence of tetrapods.Science (New York, N.Y.) · 2021Article
- Neuromodulation and Behavioral Flexibility in Larval Zebrafish: From Neurotransmitters to Circuits.Frontiers in molecular neuroscience · 2021Article
- Environmental and Molecular Modulation of Motor Individuality in Larval Zebrafish.Frontiers in behavioral neuroscience · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Binocular stereopsis requires the convergence of visual information from corresponding points in visual space seen by two different lines of sight. This may be achieved by superposition of retinal input from each eye onto the same downstream neurons via ipsi- and contralaterally projecting optic nerve fibers. Zebrafish larvae can perceive binocular cues during prey hunting but have exclusively contralateral retinotectal projections. Here we report brain activity in the tectal neuropil ipsilateral to the visually stimulated eye, despite the absence of ipsilateral retinotectal projections. This activity colocalizes with arbors of commissural neurons, termed intertectal neurons (ITNs), that connect the tectal hemispheres. ITNs are GABAergic, establish tectal synapses bilaterally and respond to small moving stimuli. ITN-ablation impairs capture swim initiation when prey is positioned in the binocular strike zone. We propose an intertectal circuit that controls execution of the prey-capture motor program following binocular localization of prey, without requiring ipsilateral retinotectal projections.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.