Evidence map›Paper›PMID 31784461›Full record

ArticleDevelopment (Cambridge, England)2019

Minimal

Matthew R George, Qiming Duan, Abigail Nagle, Irfan S Kathiriya, Yu Huang, Kavitha Rao, Saptarsi M Haldar, Benoit G Bruneau

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Epigenetics and Congenital Heart Diseases.Journal of cardiovascular development and disease · 2022
    Review
  11. LncRNAs at the heart of development and disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Review
  12. Review
  13. Article
  14. Article
  15. Deletion of aJournal of cardiovascular development and disease · 2021
    Article
  16. Epigenetics and Heart Development.Frontiers in cell and developmental biology · 2021
    Review
  17. Long Noncoding RNAs in Cardiac Development.Cold Spring Harbor perspectives in biology · 2020
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Matthew R GeorgeGladstone Institutes, San Francisco, CA 94158, USA.
Qiming DuanGladstone Institutes, San Francisco, CA 94158, USA.
Abigail NagleGladstone Institutes, San Francisco, CA 94158, USA.
Irfan S KathiriyaGladstone Institutes, San Francisco, CA 94158, USA.
Yu HuangGladstone Institutes, San Francisco, CA 94158, USA.
Kavitha RaoGladstone Institutes, San Francisco, CA 94158, USA.
Saptarsi M HaldarGladstone Institutes, San Francisco, CA 94158, USA.
Benoit G BruneauGladstone Institutes, San Francisco, CA 94158, USA benoit.bruneau@gladstone.ucsf.edu.ORCID 0000-0002-0804-7597
Gladstone Institutes · US

Funding

PREDOCTORAL TRAINING IN DEVELOPMENTAL BIOLOGYT32HD007470 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Todd Nystul · 1994 to 2026
$7.7M
Early Cardiac ProgenitorsR01HL114948 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI Benoit Gaetan Bruneau · 2013 to 2026
$7.5M
Regulation of Chromatin Signaling in Heart Failure by the BRD4 Bromodomain Protein.R01HL127240 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MCKINSEY, TIMOTHY, SRIVASTAVA, DEEPAK · 2015 to 2022
$6.4M
The Epigenetic Landscape of Heart DevelopmentUM1HL098179 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI BRUNEAU, BENOIT GAETAN, POLLARD, KATHERINE S. · 2015 to 2019
$4.7M
EXTRAMULAR RESEARCH FACILITIES CONSTRUCTIONC06RR018928 · NCRR · J. DAVID GLADSTONE INSTITUTES · PI MAHLEY, ROBERT W. · 2003 to 2003
$2.1M
NCRR NIH HHS C06 RR018928NHLBI NIH HHS R01 HL114948NHLBI NIH HHS R01 HL127240NHLBI NIH HHS UM1 HL098179NICHD NIH HHS T32 HD007470
6 · The paper itself

Abstract

Long intergenic non-coding RNAs (lincRNAs) have been implicated in gene regulation, but their requirement for development needs empirical interrogation. We computationally identified nine murine lincRNAs that have developmentally regulated transcriptional and epigenomic profiles specific to early heart differentiation. Six of the nine lincRNAs had

Indexed as

Cell DifferentiationEpigenesis, GeneticGene Expression Regulation, DevelopmentalAnimalsGene DeletionHeartHeart Defects, CongenitalMiceMice, Mutant StrainsMyocardiumRNA, Long NoncodingRNA, Long NoncodingGene regulationHeart developmentLong non-coding RNA

Identifiers

PMID31784461
PMCPMC6918742
OpenAlexW2990614888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.