Evidence map›Paper›PMID 31783850›Full record

ArticleBMC veterinary research2019

A novel PCR-based point-of-care method enables rapid, sensitive and reliable diagnosis of Babesia gibsoni infection in dogs.

I-Li Liu, Nai-Yu Chi, Chia-Ling Chang, Ming-Long Hung, Chun-Ta Chiu, Hui-Wen Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

I-Li LiuInstitute of Veterinary Clinical Science, National Taiwan University, Taipei, Taiwan.
Nai-Yu ChiCredo Biomedical Pte. Ltd., Singapore, Singapore.
Chia-Ling ChangCredo Biomedical Pte. Ltd., Singapore, Singapore.
Ming-Long HungCredo Biomedical Pte. Ltd., Singapore, Singapore.
Chun-Ta ChiuDepartment of Veterinary Medicine, National Taiwan University, 1 Sec 4 Roosevelt Rd, Taipei, Taiwan.
Hui-Wen ChenDepartment of Veterinary Medicine, National Taiwan University, 1 Sec 4 Roosevelt Rd, Taipei, Taiwan. winnichen@ntu.edu.tw.ORCID http://orcid.org/0000-0002-0595-3420
National Taiwan University · TW

Funding

Credo Biomedical Pte. Ltd. n/aNational Taiwan University n.a
6 · The paper itself

Abstract

backgroundBabesia gibsoni (B. gibsoni) is an intraerythrocytic protozoan parasite of dogs that causes fever and hemolytic illness. A timely diagnosis is essential for the disease management.

resultsHere, we report a QubeMDx PCR system which enables a rapid, sensitive and reliable diagnosis of B. gibsoni near the dog patient. Within 30 min, this diagnostic assay was able to detect as low as 0.002% parasitemia of the dog blood. Using clinical samples, this new assay was validated to demonstrate 100% agreement with real-time PCR.

conclusionsThis novel diagnostic method provides a reliable point-of-care test to assist in the identification of B. gibsoni.

Indexed as

AnimalsBabesiaBabesiosisDog DiseasesDogsPoint-of-Care SystemsReal-Time Polymerase Chain ReactionSensitivity and SpecificityBabesia gibsoniPoint-of-careQubeMDx PCR systemReal-time PCR

Identifiers

PMID31783850
PMCPMC6884907
OpenAlexW2991640646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.