Evidence map›Paper›PMID 31783577›Full record

ReviewCancers2019

Occupational Chemical Exposure and Breast Cancer Risk According to Hormone Receptor Status: A Systematic Review.

Veruscka Leso, Maria Luigia Ercolano, Dante Luigi Cioffi, Ivo Iavicoli

Abstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Residential Proximity to NPL Superfund Sites and High Particulate Matter Exposure Is Associated with Increased Likelihood of Triple-Negative Breast Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. 3Cancers · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Veruscka LesoDepartment of Public Health, Section of Occupational Medicine, University of Naples Federico II, Via S.Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-3039-2856
Maria Luigia ErcolanoDepartment of Public Health, Section of Occupational Medicine, University of Naples Federico II, Via S.Pansini 5, 80131 Naples, Italy.
Dante Luigi CioffiDepartment of Public Health, Section of Occupational Medicine, University of Naples Federico II, Via S.Pansini 5, 80131 Naples, Italy.
Ivo IavicoliDepartment of Public Health, Section of Occupational Medicine, University of Naples Federico II, Via S.Pansini 5, 80131 Naples, Italy.ORCID 0000-0003-0444-3792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancers include a heterogeneous group of diseases with clinical behaviors that may vary according to the hormonal receptor status. However, limited knowledge is available on the role of breast cancer environmental and occupational risk factors in the onset of specific molecular disease phenotypes. Therefore, the aim of this review was to provide an overview on the possible correlation between occupational chemical exposures and breast cancers with a specific receptor pattern. Pubmed, Scopus, and ISI Web of Science databases were systematically reviewed to identify all the studies addressing chemical exposure in workplaces and risk of breast cancer classified according to the presence of estrogen and/or progesterone receptors. Some positive associations were reported between solvent, polycyclic aromatic hydrocarbon, organophosphoric insecticide, and synthetic fiber exposure and estrogen receptor-positive cases, while other investigations demonstrated a relationship with receptor-negative tumors or failed to detect any significant effect. Overall, further investigation should overcome limitations due to the self-reported information on work histories, the chemical classification in general categories, and the lack of environmental or biological monitoring exposure data. This may support the development of suitable and individually "tailored" occupational risk assessment and management strategies to protect the health of exposed workers, particularly those with hypersusceptibility conditions.

Indexed as

breast cancerestrogen receptorhormone receptor statusoccupational chemical exposureprogesterone receptorrisk managementworkplace risk factors

Identifiers

PMID31783577
PMCPMC6966433

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.