Evidence map›Paper›PMID 31783535›Full record

ArticleMolecules (Basel, Switzerland)2019

A Switch between Antioxidant and Prooxidant Properties of the Phenolic Compounds Myricetin, Morin, 3',4'-Dihydroxyflavone, Taxifolin and 4-Hydroxy-Coumarin in the Presence of Copper(II) Ions: A Spectroscopic, Absorption Titration and DNA Damage Study.

Klaudia Jomová, Lenka Hudecova, Peter Lauro, Miriama Simunkova, Saleh H Alwasel, Ibrahim M Alhazza, Marian Valko

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 165 citations in OpenAlex.

  1. Interfacial Redox Engineering of TiOMolecules (Basel, Switzerland) · 2026
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Klaudia JomováDepartment of Chemistry, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia.
Lenka HudecovaDepartment of Chemistry, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia.
Peter LauroDepartment of Chemistry, Constantine the Philosopher University in Nitra, 949 74 Nitra, Slovakia.
Miriama SimunkovaFaculty Chemical and Food Technology, Slovak University of Technology, 812 37 Bratislava, Slovakia.
Saleh H AlwaselKing Saud University, Zoology Department, College of Science, Riyadh 11451, Saudi Arabia.
Ibrahim M AlhazzaKing Saud University, Zoology Department, College of Science, Riyadh 11451, Saudi Arabia.
Marian ValkoFaculty Chemical and Food Technology, Slovak University of Technology, 812 37 Bratislava, Slovakia.
Constantine the Philosopher University in Nitra · SKKing Saud University · SASlovak University of Technology in Bratislava · SK

Funding

Agentúra na Podporu Výskumu a Vývoja APVV-15-0079Researchers Supporting Project RSP-2019/59VEGA 1/0686/17
6 · The paper itself

Abstract

The beneficial effects of polyphenols, predominantly in the context of oxidative stress-related diseases such as cancer, cardiovascular diseases and neurological conditions including Alzheimer's and Parkinson's diseases, have been documented by a number of papers and reviews. The antioxidant/prooxidant properties of phenolic compounds are related mainly to the number and positions of hydroxyl groups and to their redox metal (Cu, Fe) chelating capacity. In this work we studied structurally distinct phenolic molecules such as myricetin, morin, 3',4'-dihydroxy-flavone, taxifolin and 4-hydroxycoumarin, either alone or as interacting with Cu

Indexed as

Antineoplastic AgentsAntioxidantsChelating AgentsCopperCoumarinsDNA DamageElectron Spin Resonance SpectroscopyFlavonesFlavonoidsHumansHydroxyl RadicalIonsPhotoelectron SpectroscopyPolyphenolsQuercetinReactive Oxygen Species3',4'-dihydroxyflavoneAntineoplastic AgentsAntioxidantsChelating AgentsCoppercoumarinCoumarinsFlavonesFlavonoidsHydroxyl RadicalIonsmorinmyricetinPolyphenolsQuercetinReactive Oxygen SpeciestaxifolinantioxidantcopperDNA damageflavonoidshydroxyl groupsprooxidant

Identifiers

PMID31783535
PMCPMC6930463
OpenAlexW2991164219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.