Evidence map›Paper›PMID 31783155›Full record

ReviewThe Journal of steroid biochemistry and molecular biology2020

Vitamin D and the nutritional environment in functions of intestinal stem cells: Implications for tumorigenesis and prevention.

Wenge Li, Karina Peregrina, Michele Houston, Leonard H Augenlicht

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of steroid biochemistry and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Dietary and metabolic effects on intestinal stem cells in health and disease.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Analysis of 1,25-Dihydroxyvitamin DMolecular and cellular biology · 2020
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wenge LiDepartment of Medicine, Albert Einstein College of Medicine 1300 Morris Park Ave, Bronx, NY 10461, United States.
Karina PeregrinaDepartment of Medicine, Albert Einstein College of Medicine 1300 Morris Park Ave, Bronx, NY 10461, United States.
Michele HoustonDepartment of Medicine, Albert Einstein College of Medicine 1300 Morris Park Ave, Bronx, NY 10461, United States.
Leonard H AugenlichtDepartment of Medicine, Albert Einstein College of Medicine 1300 Morris Park Ave, Bronx, NY 10461, United States; Department of Cell Biology, Albert Einstein College of Medicine 1300 Morris Park Ave, Bronx, NY 10461, United States. Electronic address: leonard.augenlicht@einstein.yu.edu.
Albert Einstein College of Medicine · US

Funding

WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI THOMAS E ROHAN · 1985 to 2026
$111.2M
Age and Diet: Major interacting factors that drive sporadic intestinal cancerR01CA174432 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AUGENLICHT, LEONARD H · 2014 to 2018
$3.3M
Nutritionally Driven Sporadic Intestinal Tumors: Impact on Stem CellsR01CA229216 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AUGENLICHT, LEONARD H · 2018 to 2022
$2.4M
A Major Nutritional Effect on Intestinal Stem Cells and TumorsR01CA214625 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI AUGENLICHT, LEONARD H · 2018 to 2022
$1.6M
NCI NIH HHS P30 CA013330NCI NIH HHS R01 CA174432NCI NIH HHS R01 CA214625NCI NIH HHS R01 CA229216
6 · The paper itself

Abstract

Sporadic colon cancer accounts for ∼80% of CRC, with high incidence in western societies strongly linked to dietary patterns. The only mouse model for sporadic CRC results from feeding mice a purified rodent western-style diet (NWD1), establishing mouse intake of several common nutrients that mimic for each its level consumed in western populations at higher risk for colon cancer (higher fat, lower vitamin D

Indexed as

AnimalsCarcinogenesisCell Transformation, NeoplasticDiet, WesternHumansIntestinal MucosaIntestinal NeoplasmsIntestinesMetabolic Networks and PathwaysStem CellsVitamin DVitamin DIntestinal homeostasisIntestinal stem cellsIntestinal tumorsNutritional environmentVitamin D

Identifiers

PMID31783155
PMCPMC7093817
OpenAlexW2989685974

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.