Evidence map›Paper›PMID 31783153›Full record

ArticleThe Journal of steroid biochemistry and molecular biology2020

A mouse model for vitamin D-induced human cathelicidin antimicrobial peptide gene expression.

Malcolm B Lowry, Chunxiao Guo, Yang Zhang, Mary L Fantacone, Isabelle E Logan, Yan Campbell, Weijian Zhang, Mai Le, Arup K Indra, Gitali Ganguli-Indra and 4 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of steroid biochemistry and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 55 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Airway epithelium in lung transplantation: a potential actor for post-transplant complications?European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Cholecalciferol Exhibits no Antibacterial Effect onRecent advances in anti-infective drug discovery · 2024
    Article
  13. bioRxiv : the preprint server for biology · 2023
    Article
  14. Effective Healing ofInternational journal of molecular sciences · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Malcolm B LowryDepartment of Microbiology, Oregon State University, Corvallis, OR 97331, USA; Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA.
Chunxiao GuoLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA.
Yang ZhangLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA; Nutrition Graduate Program, School of Biological & Population Health Sciences, College of Public Health & Human Sciences, Oregon State University, Corvallis, OR 97331, USA.
Mary L FantaconeLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA.
Isabelle E LoganLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA.
Yan CampbellLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA.
Weijian ZhangLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA.
Mai LeDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, OR 97331, USA.
Arup K IndraDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA; Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, OR 97331, USA; Knight Cancer Institute, OHSU, Portland, OR 97239, USA; Department of Dermatology, Oregon Health & Science University (OHSU), Portland, OR 97239, USA.
Gitali Ganguli-IndraDepartment of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Corvallis, OR 97331, USA; Knight Cancer Institute, OHSU, Portland, OR 97239, USA.
Jingwei XieDepartment of Surgery, Transplant & Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Richard L GalloDepartment of Dermatology, University of California San Diego, La Jolla, CA 92093, USA.
H Phillip KoefflerDivision of Hematology/Oncology, Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90048, USA; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.
Adrian F GombartLinus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA. Electronic address: adrian.gombart@oregonstate.edu.
Oregon State University · USNational University of Singapore · SGOHSU Knight Cancer InstituteUniversity of California, San Diego · USUniversity of Nebraska Medical Center · US

Funding

REGULATION OF HEMATOPOIETIC CYTOKINESR01CA026038 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KOEFFLER, HAROLD PHILLIP · 1985 to 2013
$4.7M
Cathelicidin in Skin ImmunityR37AI052453 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard L Gallo, Victor Nizet · 2019 to 2026
$4.6M
Vitamin D, Xanthohumol and Nuclear Receptors: Targeting Immunity, Microbiota andR01AT009168 · NCCIH · OREGON STATE UNIVERSITY · PI GOMBART, ADRIAN FRIEDRICH, MAIER, CLAUDIA S · 2015 to 2019
$3.0M
Nanofiber-based Delivery of Combined Immune-modulating Compounds to Minimize Infection and Enhance Wound HealingR01GM123081 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI XIE, JINGWEI · 2017 to 2024
$2.8M
Inflammatory cross-talk between skin and gutR01DK128787 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALLO, RICHARD L, SALZMAN, NITA H · 2021 to 2024
$2.6M
Conflict and Cooperation between AMP Species on the skinR01AR076082 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GALLO, RICHARD L, NAKATSUJI, TERUAKI · 2019 to 2023
$2.3M
Regulating Cathelicidin Expression for Disease TherapyR01AI065604 · NIAID · OREGON STATE UNIVERSITY · PI GOMBART, ADRIAN FRIEDRICH · 2007 to 2011
$2.1M
NCCIH NIH HHS R01 AT009168NCI NIH HHS R01 CA026038NIAID NIH HHS R01 AI065604NIAID NIH HHS R37 AI052453NIAMS NIH HHS R01 AR076082NIDDK NIH HHS R01 DK128787NIGMS NIH HHS R01 GM123081
6 · The paper itself

Abstract

In humans and other primates, 1,25(OH)

Indexed as

AnimalsAntimicrobial Cationic PeptidesCathelicidinsCholecalciferolFemaleGene Expression ProfilingGene Expression RegulationHumansImmunity, InnateLipopolysaccharidesMacrophagesMaleMiceMice, Inbred C57BLMice, Inbred DBAMice, TransgenicAntimicrobial Cationic PeptidesCathelicidinsCholecalciferolLipopolysaccharidesVitamin DCathelicidinCyp27b1Innate immunityMacrophageTLRVitamin D

Identifiers

PMID31783153
PMCPMC7089838
OpenAlexW2990966408

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.