Evidence map›Paper›PMID 31783150›Full record

ArticleThe Journal of steroid biochemistry and molecular biology2020

1α, 25 Dihydroxyvitamin D (1,25(OH)

J C Fleet, G N Burcham, R D Calvert, B D Elzey, T L Ratliff

Open access · greenAbstract read
In one paragraph

Article in The Journal of steroid biochemistry and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  16. MDSC: a new potential breakthrough in CAR-T therapy for solid tumors.Cell communication and signaling : CCS · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

J C FleetDepartment of Nutrition Science, Purdue University, West Lafayette, IN, United States; Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN, United States. Electronic address: fleet@purdue.edu.
G N BurchamDepartment of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States.
R D CalvertDepartment of Nutrition Science, Purdue University, West Lafayette, IN, United States.
B D ElzeyDepartment of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States; Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN, United States.
T L RatliffDepartment of Comparative Pathobiology, Purdue University, West Lafayette, IN, United States; Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN, United States.
Purdue University West Lafayette · USCenter for Cancer Research · US

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI John Tesmer · 1985 to 2026
$43.4M
Initiation and Regulation of Chronic Autoimmune Prostate InflammationR01DK084454 · NIDDK · PURDUE UNIVERSITY · PI RATLIFF, TIMOTHY L. · 2009 to 2015
$2.0M
BD Fortessa Flow Cytometer for Multi-User Shared FacilityS10OD020029 · OD · PURDUE UNIVERSITY · PI RATLIFF, TIMOTHY L. · 2015 to 2015
$412k
Research Training for Veterinarians in Comparative PathobiologyT32OD011122 · OD · PURDUE UNIVERSITY · PI HOGENESCH, HARM · 2012 to 2014
$362k
NCI NIH HHS P30 CA023168NIDDK NIH HHS R01 DK084454NIH HHS S10 OD020029NIH HHS T32 OD011122
6 · The paper itself

Abstract

Myeloid derived suppressor cells (MDSC) suppress the ability of cytotoxic T cells to attack and clear tumor cells from the body. The active form of vitamin D, 1,25 dihydroxyvitamin D (1,25(OH)

Indexed as

AnimalsCell Line, TumorCells, CulturedImmune ToleranceMaleMice, Inbred C57BLMyeloid-Derived Suppressor CellsNeoplasmsReceptors, CalcitriolT-LymphocytesVitamin DVitamins1,25-dihydroxyvitamin DReceptors, CalcitriolVitamin DVitaminsCancerImmunologyMyeloid derived suppressor cellVitamin D receptor

Identifiers

PMID31783150
PMCPMC8041088
OpenAlexW2989780526

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.