Evidence map›Paper›PMID 31782986›Full record

ArticleJournal of the American Chemical Society2020

An Organometallic Strategy for Assembling Atomically Precise Hybrid Nanomaterials.

Julia M Stauber, Elaine A Qian, Yanxiao Han, Arnold L Rheingold, Petr Král, Daishi Fujita, Alexander M Spokoyny

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Redox-Active Boron Clusters.Accounts of chemical research · 2024
    Article
  8. Article
  9. Review
  10. OrganometallicBioconjugate chemistry · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. ElectrooxidativeChemical science · 2021
    Article
  16. Article
  17. An Organometallic Strategy for Cysteine Borylation.Journal of the American Chemical Society · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julia M StauberDepartment of Chemistry and Biochemistry , University of California, Los Angeles , Los Angeles , California 90095 , United States.ORCID 0000-0001-9783-907X
Elaine A QianDepartment of Chemistry and Biochemistry , University of California, Los Angeles , Los Angeles , California 90095 , United States.ORCID 0000-0002-7111-7383
Yanxiao HanDepartment of Chemistry , University of Illinois at Chicago , Chicago , Illinois 60607 , United States.ORCID 0000-0002-1684-6073
Arnold L RheingoldDepartment of Chemistry and Biochemistry , University of California, San Diego , La Jolla , California 92093 , United States.
Petr KrálDepartment of Chemistry , University of Illinois at Chicago , Chicago , Illinois 60607 , United States.ORCID 0000-0003-2992-9027
Daishi FujitaInstitute for Integrated Cell-Material Sciences , Kyoto University , Kyoto 606-8302 , Japan.
Alexander M SpokoynyDepartment of Chemistry and Biochemistry , University of California, Los Angeles , Los Angeles , California 90095 , United States.ORCID 0000-0002-5683-6240

Funding

Inorganic Chemistry Tools for Bioconjugation, Recognition and ImagingR35GM124746 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Alexander Michael Spokoyny · 2017 to 2026
$4.0M
NIGMS NIH HHS R35 GM124746
6 · The paper itself

Abstract

For decades, chemists have strived to mimic the intricate design and diverse functions of naturally occurring systems through the bioinspired synthesis of programmable inorganic nanomaterials. The development of thiol-capped gold nanoparticles (AuNPs) has driven advancement in this area; however, although versatile and readily accessible, hybrid AuNPs are rarely atomically precise, which limits control over their surface topology and therefore the study of complex structure-function relationships. Here, we present a bottom-up approach to the systematic assembly of atomically precise hybrid nanoclusters employing a strategy that mimics the synthetic ease with which thiol-capped AuNPs are normally constructed, while producing well-defined covalent nanoscale assemblies with diverse surface topologies. For the first time, using a structurally characterized cluster-based organometallic building block, we demonstrate the systematic synthesis of nanoclusters with multivalent binding capabilities to complex protein targets.

Indexed as

GoldMagnetic Resonance SpectroscopyMetal NanoparticlesOrganometallic CompoundsSpectrometry, Mass, Electrospray IonizationGoldOrganometallic Compounds

Identifiers

PMID31782986
PMCPMC7262991

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.