ArticleJournal of sleep research2020
Trajectories of daytime sleepiness and their associations with dementia incidence.
Article in Journal of sleep research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Sleep disorders and the risk of cognitive decline or dementia: an updated systematic review and meta-analysis of longitudinal studies.Journal of neurology · 2025Pooled it
- Effect of Excessive Daytime Sleepiness and Long Sleep Duration on All Cause Dementia: A Systematic Review and Meta-analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Pooled it
- Associations of adherence to a healthy sleep pattern with the dementia risk in the UK biobank.Alzheimer's research & therapy · 2025Article
- Olfactory Dysfunction and Long-Term Trajectories of Sleep Disorders among early Parkinson's Disease: Findings from a Longitudinal Cohort.Neuroepidemiology · 2025Article
- Sleep and geriatric syndromes in elderly emergency patients in China: a cross-sectional survey.PeerJ · 2025Article
- Association Between Daytime Sleepiness and Quality of Life in Chinese Adolescents: A Moderated Mediation of Cognitive Dysfunction and Depressive Symptoms.Neuropsychiatric disease and treatment · 2025Article
- Association of Sleep Disturbances With Prevalent and Incident Motoric Cognitive Risk Syndrome in Community-Residing Older Adults.Neurology · 2024Article
- The association between sleep duration trajectories and successful aging: a population-based cohort study.BMC public health · 2024Article
- Association between dysphagia risk and sleep quality in community-dwelling older adults: A cross-sectional study.Heliyon · 2024Article
- How Modifiable Are Modifiable Dementia Risk Factors? A Framework for Considering the Modifiability of Dementia Risk Factors.The journal of prevention of Alzheimer's disease · 2024Review
- The prevalence of excessive daytime sleepiness and associated factors in older diabetic patients.Aging clinical and experimental research · 2023Article
- Circadian disruption and sleep disorders in neurodegeneration.Translational neurodegeneration · 2023Review
- A high propensity for excessive daytime sleepiness independent of lifestyle is associated with cognitive performance in community-dwelling older adults.Frontiers in psychiatry · 2023Article
- Article
- Social Support and Daytime Sleepiness Among Chinese Medical Students: Mediating Roles of Loneliness and Problematic Smartphone Use.Psychology research and behavior management · 2023Article
- Article
- The Relationship Between Light Exposure before Bedtime and Daytime Sleepiness Among People Living With Cognitive Impairment.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022Article
- Disease progression in Parkinson's disease patients with subjective cognitive complaint.Annals of clinical and translational neurology · 2021Article
- Cognitive Functions Predict Trajectories of Sleepiness Over 10 Years: A Population-Based Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Several studies have associated daytime sleepiness with risk of dementia, but it is unknown whether longstanding and emerging daytime sleepiness equally signal a risk of dementia, and whether other health factors explain these associations. In a prospective, population-based epidemiologic study, we (i) assessed associations of daytime sleepiness trajectories over 10 years with dementia incidence and (ii) examined whether selected health characteristics attenuated these associations. Using latent group-based trajectory analysis we categorized participants into three groups: (i) no daytime sleepiness (n = 959, 49.2%), (ii) emerging daytime sleepiness (n = 342, 17.5%) and (iii) persistent daytime sleepiness (n = 650, 33.3%). Compared with no daytime sleepiness, emerging and persistent daytime sleepiness were similarly associated with greater incident dementia risk (respective hazard ratios [95% confidence intervals] were 2.2 [1.3, 3.5] and 1.9 [1.2, 3.1]). Baseline blood pressure, body mass index, chronic disease diagnoses and symptoms of depression did not attenuate these associations. In contrast, lack of independence in instrumental activities of daily living attenuated the daytime sleepiness-dementia association by approximately 17%-21%. These findings suggest that persistent and emerging daytime sleepiness may signal a risk of dementia. However, the underlying mechanisms remain unclear. Further studies should investigate whether and how pathways to sleepiness, functional impairment and dementia pathophysiology interrelate and manifest together over time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.