Evidence map›Paper›PMID 31782109›Full record

ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2020

Safety and efficacy of balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension in the Netherlands.

M C J van Thor, R J Lely, N J Braams, L Ten Klooster, M A M Beijk, R H Heijmen, D A F van den Heuvel, B J W M Rensing, R J Snijder, A Vonk Noordegraaf and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

M C J van ThorDepartment of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands. mc.van.thor@antoniusziekenhuis.nl.
R J LelyDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
N J BraamsDepartment of Pulmonary Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
L Ten KloosterDepartment of Pulmonary Medicine, St. Antonius Hospital, Nieuwegein, The Netherlands.
M A M BeijkDepartment of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
R H HeijmenDepartment of Cardiothoracic surgery, St. Antonius Hospital, Nieuwegein, The Netherlands.
D A F van den HeuvelDepartment of Radiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
B J W M RensingDepartment of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
R J SnijderDepartment of Pulmonary Medicine, St. Antonius Hospital, Nieuwegein, The Netherlands.
A Vonk NoordegraafDepartment of Pulmonary Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
E J NossentDepartment of Pulmonary Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
L J MeijboomDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
P SymerskyDepartment of Cardiothoracic surgery, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
J J MagerDepartment of Pulmonary Medicine, St. Antonius Hospital, Nieuwegein, The Netherlands.
H J BogaardDepartment of Pulmonary Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
M C PostDepartment of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
St. Antonius Ziekenhuis · NLAmsterdam University Medical Centers · NLVrije Universiteit Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBalloon pulmonary angioplasty (BPA) is an emerging treatment in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and chronic thromboembolic disease (CTED). We describe the first safety and efficacy results of BPA in the Netherlands.

methodsWe selected all consecutive patients with inoperable CTEPH and CTED accepted for BPA treatment who had a six-month follow-up in the St. Antonius Hospital in Nieuwegein and the Amsterdam University Medical Center (UMC) in Amsterdam. Functional class (FC), N‑terminal pro-brain natriuretic peptide (NT-proBNP), 6‑minute walking test distance (6MWD) and right-sided heart catheterisation were performed at baseline and six months after last BPA. Complications for each BPA procedure were noted.

resultsA hundred and seventy-two BPA procedures were performed in 38 patients (61% female, mean age 65 ± 15 years). Significant improvements six months after BPA treatment were observed for functional class (63% FC I/II to 90% FC I/II, p = 0.014), mean pulmonary artery pressure (-8.9 mm Hg, p = 0.0001), pulmonary vascular resistance (-2.8 Woods Units (WU), p = 0.0001), right atrial pressure (-2.0 mm Hg, p = 0.006), stroke volume index (+5.7 ml/m

conclusionsBPA performed in a CTEPH expert centre is an effective and safe treatment in patients with inoperable CTEPH.

Indexed as

Balloon pulmonary angioplastyChronic thromboembolic pulmonary hypertensionClinical outcomeEfficacySafety

Identifiers

PMID31782109
PMCPMC6977797
OpenAlexW2989972057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.