Evidence map›Paper›PMID 31782108›Full record

ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2020

Prophylactic veno-arterial extracorporeal membrane oxygenation in patients undergoing high-risk percutaneous coronary intervention.

F S van den Brink, T A Meijers, S H Hofma, A J van Boven, A Nap, A Vonk, P Symersky, K D Sjauw, P Knaapen

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05387902 (Short-term Outcomes of Elective High-risk PCI With Extracorporeal Membrane Oxygenation Support), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05387902 completednot on this mapstarted 2022, after this paper: background citation

Short-term Outcomes of Elective High-risk PCI With Extracorporeal Membrane Oxygenation Support: a Single-centre Registry

Typeobservational_patient_registrySponsorRobert Jan van GeunsRan2022 to 2022Enrolled25ConditionsCoronary Artery DiseaseArmsExtracorporeal Membrane Oxygenation
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) in high-risk (HR) percutaneous coronary intervention (PCI).Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026
    Article
  3. Review
  4. Article
  5. Mechanical circulatory support for complex, high-risk percutaneous coronary intervention.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Observational
  12. Article
  13. Review
  14. Review
  15. Article
  16. Observational
  17. Observational
  18. Article
  19. Article
  20. Venoarterial extracorporeal membrane oxygenation in elective high-risk percutaneous coronary intervention: a viable option?Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

F S van den BrinkDepartment of Cardiology, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands. floris.s.van.den.brink@gmail.com.
T A MeijersDepartment of Cardiology, Location Vrije Universiteit Medisch Centrum, Amsterdam Universitair Medisch Centrum, Amsterdam, The Netherlands.
S H HofmaDepartment of Cardiology, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands.
A J van BovenDepartment of Cardiology, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands.
A NapDepartment of Cardiology, Location Vrije Universiteit Medisch Centrum, Amsterdam Universitair Medisch Centrum, Amsterdam, The Netherlands.
A VonkDepartment of Cardiology, Location Vrije Universiteit Medisch Centrum, Amsterdam Universitair Medisch Centrum, Amsterdam, The Netherlands.
P SymerskyDepartment of Cardio-Thoracic Surgery, Location Vrije Universiteit Medisch Centrum, Amsterdam Universitair Medisch Centrum, Amsterdam, The Netherlands.
K D SjauwDepartment of Cardiology, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands.
P KnaapenDepartment of Cardiology, Location Vrije Universiteit Medisch Centrum, Amsterdam Universitair Medisch Centrum, Amsterdam, The Netherlands.
Medisch Centrum Leeuwarden · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeComplex high-risk percutaneous coronary intervention (PCI) is challenging and frequently accompanied by haemodynamic instability. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can provide cardiopulmonary support in high-risk PCI. However, the outcome is unclear.

methodsA two-centre, retrospective study was performed of all patients undergoing high-risk PCI and receiving VA-ECMO for cardiopulmonary support.

resultsA total of 14 patients (92% male, median age 69 (53-83) years), of whom 50% had previous coronary artery disease in the form of a coronary artery bypass graft (36%) and a PCI (14%) underwent high-risk PCI and received VA-ECMO support. The main target lesion was a left main coronary artery in 78%, a left anterior descending artery in 14%, a right coronary artery in 7%, and 71% underwent multi-vessel PCI in addition to main target vessel PCI. The median SYNTAX score was 27.2 (8-42.5) and in 64% (9/14) there was a chronic total occlusion. Left ventricular function was mildly impaired in 7% (1/14), moderately impaired in 14% (2/14) and severely impaired in 64% (9/14). Cannulation was femoral-femoral in all patients. Median ECMO run was 2.57 h (1-4). Survival was 93% (13/14). One patient died during hospitalisation due to refractory cardiac failure. All other patients survived to discharge. Complications occurred in 14% (2/14), with one patient developing a transient ischaemic attack post-ECMO and one patient developing a thrombus in the femoral vein used for ECMO cannulation.

conclusionVA-ECMO in high-risk PCI is feasible with a good outcome. It can be successfully used for cardiopulmonary support in selected patients.

Indexed as

Chronic total occlusionHigh-risk percutaneous coronary interventionPercutaneous coronary interventionVeno-arterial extracorporeal membrane oxygenation

Identifiers

PMID31782108
PMCPMC7052097
OpenAlexW2991211873

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.