Evidence map›Paper›PMID 31781883›Full record

ArticleTechniques in coloproctology2019

Implementation of laser ablation of fistula tract (LAFT) for perianal fistulas: do the results warrant continued application of this technique?

J Stijns, Y T van Loon, S H E M Clermonts, K W Gӧttgens, D K Wasowicz, D D E Zimmerman

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Article in Techniques in coloproctology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Core-Out Fistulectomy Combined With Laser Ablation of the Trans-Sphincteric Fistula Tract: A Pilot Study of Efficacy and Safety.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Treatment of anal fistula with FiLaCTechniques in coloproctology · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Modern surgical strategies for perianal Crohn's disease.World journal of gastroenterology · 2020
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J StijnsDepartment of Surgery, ETZ (Elisabeth TweeSteden) Hospital, Doctor Deelenlaan 5, 5042 AD, Tilburg, The Netherlands.
Y T van LoonDepartment of Surgery, ETZ (Elisabeth TweeSteden) Hospital, Doctor Deelenlaan 5, 5042 AD, Tilburg, The Netherlands.
S H E M ClermontsDepartment of Surgery, ETZ (Elisabeth TweeSteden) Hospital, Doctor Deelenlaan 5, 5042 AD, Tilburg, The Netherlands.
K W GӧttgensDepartment of Surgery, ETZ (Elisabeth TweeSteden) Hospital, Doctor Deelenlaan 5, 5042 AD, Tilburg, The Netherlands.
D K WasowiczDepartment of Surgery, ETZ (Elisabeth TweeSteden) Hospital, Doctor Deelenlaan 5, 5042 AD, Tilburg, The Netherlands.
D D E ZimmermanDepartment of Surgery, ETZ (Elisabeth TweeSteden) Hospital, Doctor Deelenlaan 5, 5042 AD, Tilburg, The Netherlands. d.zimmerman@etz.nl.ORCID http://orcid.org/0000-0002-0393-9350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaser Ablation of Fistula Tract (LAFT) is a novel technique for the treatment of perianal fistulas. Initial reports have shown moderate-to-good results. The aim of this study was to evaluate this implementation and the effectiveness of this technique. Patients were offered LAFT as a treatment option for their perianal fistulas at the outpatient clinic between November 2016 and April 2018. Inclusion criteria were intersphincteric and transsphincteric fistula of cryptoglandular origin [10]. Exclusion criteria were supra- or extrasphincteric fistula, Crohn's disease, presence of undrained collections or side tracts and malignancy-related fistula. The primary outcome was fistula healing rate, the main secondary outcome incidence of postoperative fecal incontinence. Healing and postoperative FISI were evaluated at our outpatient clinic during follow-up at 6 and 12 weeks. A questionnaire was sent to all patients to evaluate the long-term postoperative FISI and patient satisfaction after 3 months.

resultsBetween November 2016 and April 2018, 20 patients [m:f = 4:16, median age 45 (27-78) years] underwent LAFT. Median follow-up was 10 months (IQR 7.3 months). A draining seton was placed in 15 (75%) of all patients with a median time of 12 weeks (IQR 14 weeks) prior to LAFT. Five intersphincteric and 13 transsphincteric fistulas were treated. Overall healing rate was 20% (4/20). The median postoperative fecal incontinence severity index (FISI) score was 0 (range 0-38); however, we found a change in continence in 39% of the patients.

conclusionsLAFT has now been discontinued as a treatment of cryptoglandular perianal fistulas in our centre, because of its disappointing results. Further detailed research seems to be warranted to investigate its exact indication and limitations.

Indexed as

Laser TherapyAdultAgedAnus DiseasesCutaneous FistulaFecal IncontinenceFemaleHumansMaleMiddle AgedPatient SatisfactionPostoperative ComplicationsRectal FistulaSeverity of Illness IndexSurveys and QuestionnairesTreatment OutcomeCryptoglandularFiLaCIntersphinctericLAFTPerianal fistulaTranssphincteric

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.